Is nucleate cell count and neutrophil to lymphocyte ratio related to patients with audiographically distinct sudden sensorineural hearing loss?

Medicine
Yuanyuan SunShankai Yin

Abstract

The aim of this study was to investigate the possible relationships between sudden sensorineural hearing loss (SSNHL) patients with distinct audiographic data and nucleate cell count and neutrophil to lymphocyte ratio (NLR).SSNHL patients differed in audiographic curves were included, 40 with low-frequency SSNHL (LF-SSNHL), 33 with high-frequency SSNHL (HF-SSNHL), 36 with all-frequency SSNHL (AF-SSNHL), 34 with total-deafness SSNHL (TD-SSNHL), and 31 age- and sex-matched healthy controls. Peripheral venous blood samples were collected and nucleate cell such as white blood cell (WBC), neutrophil and lymphocyte, and NLR were measured. Each group was divided into recovery and unrecovery subgroup according to hearing levels after 1-month therapy, and then compared the difference of the count of WBC, neutrophil and lymphocyte, and NLR between the 2 subgroups.The WBC count of the HF-SSNHL, AF-SSNHL, and TD-SSNHL group was significantly higher than that of the control group (P = .024, P = .003, P = .008, respectively), not for LF-SSNHL group (P = .248). WBC count between LF-SSNHL and AF-SSNHL group was significantly different (P = .045). The neutrophil count of the HF-SSNHL, AF-SSNHL, and TD-SSNHL group was significantly higher than t...Continue Reading

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Software Mentioned

GraphPad Prism
SPSS

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