Is Omentectomy Mandatory Among Early Stage (I, II) Malignant Ovarian Germ Cell Tumor Patients? A Retrospective Study of 223 Cases

International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society
Wenyan Xu, Yanfang Li

Abstract

The aim of the study was to investigate whether omentectomy (OMT) is necessary in the operation for apparently early stage malignant ovarian germ cell tumors (MOGCTs). Searching medical records database of Sun Yat-sen University Cancer Center from January 1, 1966, to November 30, 2015, patients with MOGCTs were identified and their age, year of diagnosis, tumor grade, histologic subtype, International Federation of Gynecology and Obstetrics stage, nodal findings, gross observation of omentum, and performance of OMT were assessed. Overall survivals of patients with or without OMT were compared using Kaplan-Meier survival curves. A total of 223 MOGCT cases with clinically early stage (stage I and II) disease and with the 3 common histological subtypes of MOGCT were obtained, which include yolk sac tumor (YST), dysgerminoma (DSG), and immature teratoma (IMT). There were 192 stage I cases and 31 stage II cases. Fifty-four patients were diagnosed with YST, 61 with DSG, and 108 with IMT. Omentectomy was performed as part of the initial surgery in 74.0% patients (165/223) and was omitted in 26.0% patients (58/223). Chemotherapy was administered in 88.3% (197/223) of all patients. The median follow-up was 82.0 months. The 10-year overa...Continue Reading

References

May 30, 2012·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Yoshihito YokoyamaHideki Mizunuma
Mar 11, 2015·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Leah McNallyAmer Karam
Apr 23, 2016·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Xiaojing WangYanfang Li
May 3, 2016·The Australian & New Zealand Journal of Obstetrics & Gynaecology·Ting ZhaoYuan Lu

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Citations

Jan 25, 2019·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Beijiao QinYanfang Li

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