Is Pancreaticoduodenectomy Feasible for Recurrent Remnant Bile Duct Cancer Following Bile Duct Segmental Resection?

Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract
Jae Geun LeeKyung Sik Kim

Abstract

When bile duct cancer recurs after surgery, treatment options are limited. This study examines the usefulness of reoperative pancreaticoduodenectomy for recurrent cancer after initial segmental bile duct resection. Six patients (5 males, 1 females; median age 65 years) who underwent pancreaticoduodenectomy for recurrent remnant bile duct cancer following segmental bile duct resection were included: 4 underwent surgery at Severance Hospital and 2 at Gangnam Severance Hospital from January 2000 to December 2013. Medical records data were retrospectively reviewed, including demographics, type of first and second surgery, radicality of resection, TNM stage, adjuvant treatments, complications, and survival. Kaplan-Meier curves were used to analyze survival. The median interval between operations was 57 (range 7-95) months. Median operation time was 6.9 (range 5.2-12.8) h, blood loss was 400 (range 50-1170) mL, intensive care unit stay was 1 (range 1-2) day, and postoperative hospital stay was 33 (range 15-55) days. No patient died. Four had severe complications. The median survival after pancreaticoduodenectomy was 16 (range 5-89) months. Four patients had recurrence. T stage, N stage, and resection radicality influenced survival. P...Continue Reading

References

Aug 1, 1976·Current Problems in Cancer·W P Longmire
Jan 1, 1992·Annals of Surgery·H BismuthT Diamond
Jan 1, 1986·American Journal of Surgery·P A GraceW P Longmire
Apr 1, 1984·American Journal of Surgery·F AlexanderE Watkins
Feb 1, 1983·The Journal of Pathology·K Weinbren, S S Mutum
Oct 1, 1981·Annals of Surgery·R K TompkinsW P Longmire
Feb 1, 1994·Annals of Surgery·D S Tyler, D B Evans
May 1, 1994·Seminars in Liver Disease·J N Vauthey, L H Blumgart
Nov 1, 1993·The British Journal of Surgery·E M TargaronaN A Habib
Nov 1, 1996·American Journal of Surgery·E K RobinsonD B Evans
Sep 27, 2001·Annals of Surgery·W R JarnaginL H Blumgart
Apr 26, 2005·Annals of Surgery·William R JarnaginLeslie H Blumgart
May 12, 2005·Gastroenterology·Konstantinos N Lazaridis, Gregory J Gores
Jun 24, 2005·ANZ Journal of Surgery·Parul J ShuklaLuis J Desouza
Aug 27, 2005·The Annals of Thoracic Surgery·Paul H SchipperPeter C Pairolero
Apr 26, 2007·Annals of Surgery·Michelle L DeOliveiraRichard D Schulick
Feb 16, 2008·Journal of Hepato-biliary-pancreatic Surgery·Satoshi KondoUNKNOWN Japan Society of Clinical Oncology
Jun 11, 2008·Annals of Surgical Oncology·Itaru EndoWilliam R Jarnagin
Jul 31, 2008·Pancreas·Sohei SatoiUNKNOWN Department of Surgery, Kansai Medical University, Osaka, Japan
Jul 30, 2009·Annals of Surgery·Pierre A ClavienMasatoshi Makuuchi
Nov 26, 2009·The British Journal of Surgery·A KobayashiS Miyagawa
Feb 25, 2010·Annals of Surgical Oncology·Stephen B Edge, Carolyn C Compton
Jul 2, 2010·World Journal of Surgical Oncology·Yanming ZhouZhenyu Liu
Apr 13, 2012·American Journal of Clinical Oncology·Fangxuan LiQiang Xue
Jul 17, 2012·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Min Soo ChoKyung Sik Kim
Jan 29, 2013·World Journal of Surgery·Jin Hong LimWoo Jung Lee
Aug 16, 2014·American Journal of Surgery·Patryk Kambakamba, Michelle L DeOliveira
Sep 5, 2014·Annals of Surgery·Yoshihiro MiseNorihiro Kokudo

❮ Previous
Next ❯

Citations

Jun 5, 2018·Annals of Gastroenterological Surgery·Masaru MiyazakiMasayuki Ohtsuka
Feb 10, 2021·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Jun SakataToshifumi Wakai

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Korean Journal of Hepato-biliary-pancreatic Surgery
Joo Hwa KwakHui Song Lee
Hepatobiliary & Pancreatic Diseases International : HBPD INT
Qin-Song ShengJian-Jiang Lin
Gan to kagaku ryoho. Cancer & chemotherapy
Toshiaki AidaHiroshi Ito
Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract
Jeffrey M FarmaH Richard Alexander
© 2021 Meta ULC. All rights reserved