Is plasma serine a marker for psychosis?

Biological Psychiatry
G F CarlB K Young


There is some disagreement in the literature concerning the use of plasma serine concentrations as a biological marker for psychoses including schizophrenia. The groups studying this phenomenon have used different methodologies, including gas chromatography and classical amino acid analysis. In the present study, using high pressure liquid chromatography to analyze plasma amino acids from schizophrenics and controls, we found no difference in plasma serine concentrations. None of the plasma amino acid concentrations that were measured differed significantly between schizophrenics and controls but the basic amino acids tended toward higher concentrations in schizophrenics.


Apr 1, 1990·Psychiatry Research·F MacciardiE Smeraldi
Jun 1, 1986·Psychiatry Research·R Waziri, J Mott
Sep 1, 1985·Journal of Affective Disorders·R WaziriJ Wilcox
Jun 1, 1985·Psychiatry Research·T L Perry, S Hansen
Jun 1, 1984·Psychiatry Research·R WaziriJ Mott
Jul 1, 1983·The British Journal of Psychiatry : the Journal of Mental Science·R WaziriA D Sherman


Jun 1, 2003·Acta Neuropsychiatrica·F M M A van der HeijdenS Tuinier
Aug 16, 2012·Translational Psychiatry·Y HeD Rujescu
Jan 26, 2010·Psychiatry Research·Jaromir HonsJan Libiger
Apr 17, 2012·Journal of Psychiatric Research·Jaromir HonsJan Libiger
May 5, 2016·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Joshua ChiappelliL Elliot Hong
Mar 17, 2004·Current Opinion in Neurology·Tom J de Koning, Leo W J Klomp
Jan 5, 2010·Psychiatry Investigation·Vincenzo De LucaMarcellino Monda

Related Concepts

High Pressure Liquid Chromatography Procedure
Viral Markers

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Alzheimer's Disease: MS4A

Variants within the membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease in genome-wide association studies. Here is the latest research on Alzheimer's disease and MS4A.

Pediculosis pubis

Pediculosis pubis is a disease caused by a parasitic insect known as Pthirus pubis, which infests human pubic hair, as well as other areas with hair including eye lashes. Here is the latest research.

Rh Isoimmunization

Rh isoimmunization is a potentially preventable condition that occasionally is associated with significant perinatal morbidity or mortality. Discover the latest research on Rh Isoimmunization here.

Genetic Screens in iPSC-derived Brain Cells

Genetic screening is a critical tool that can be employed to define and understand gene function and interaction. This feed focuses on genetic screens conducted using induced pluripotent stem cell (iPSC)-derived brain cells. It also follows CRISPR-Cas9 approaches to generating genetic mutants as a means of understanding the effect of genetics on phenotype.

Enzyme Evolution

This feed focuses on molecular models of enzyme evolution and new approaches (such as adaptive laboratory evolution) to metabolic engineering of microorganisms. Here is the latest research.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Pharmacology of Proteinopathies

This feed focuses on the pharmacology of proteinopathies - diseases in which proteins abnormally aggregate (i.e. Alzheimer’s, Parkinson’s, etc.). Discover the latest research in this field with this feed.

Alignment-free Sequence Analysis Tools

Alignment-free sequence analyses have been applied to problems ranging from whole-genome phylogeny to the classification of protein families, identification of horizontally transferred genes, and detection of recombined sequences. Here is the latest research.

Related Papers

Progress in Neuro-psychopharmacology & Biological Psychiatry
A LuccaV Lucini
Clinica Chimica Acta; International Journal of Clinical Chemistry
Masayuki TomiyaToshimasa Toyo'oka
© 2021 Meta ULC. All rights reserved