PMID: 1681217Oct 5, 1991

Is postoperative delirium related to reduced plasma tryptophan?

Lancet
R C van der MastL Pepplinkhuizen

Abstract

The cause of postoperative delirium is unknown. In 7 patients with postcardiotomy delirium (6 men, 1 woman; mean age 67 years), we observed a plasma concentration of tryptophan and a plasma tryptophan ratio significantly lower than in 8 non-delirious postoperative control patients. We suggest that the mental symptoms of postcardiotomy delirium are the consequence of a reduced cerebral tryptophan availability due to a catabolic state.

References

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Citations

Sep 1, 1996·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·S M OlofssonC A Meyers
Mar 12, 2008·Psychopharmacology·Marco BortolatoRoberto Stancampiano
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Related Concepts

Subacute Delirium
Cardiac Surgery Procedures
PMS-Tryptophan

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