Is pre-operative axillary ultrasound alone sufficient to determine need for axillary dissection in early breast cancer patients?

Medicine
Suniza JamarisNur Aishah Mohd Taib

Abstract

Pre-operative status of axillary lymph node (ALN) in early breast cancer is usually initially assessed by pre-operative ultrasound, followed by ultrasound-guided needle biopsy (UNB) confirmation. Patients with positive nodal status will undergo axillary lymph node dissection (ALND), while those with negative nodal status will have sentinel lymph node biopsy. ALND is associated with higher morbidity than Sentinel lymph node biopsy. The objective of this study is to determine if axillary ultrasound alone without UNB is predictive enough to assign patients to ALND and to identify ultrasound features that are significantly associated with pathologically positive ALN.383 newly diagnosed primary breast cancer patients between 2012 and 2014, and who had undergone pre-operative axillary ultrasound in University Malaya Medical Centre with a complete histopathology report of the axillary surgery were retrospectively reviewed. ALN was considered positive if it had any of these features: cortical thickening > 3 mm, loss of fatty hilum, hypoechoic solid node, mass-like appearance, round shape and lymph node size > 5 mm. Post-operative histopathological reports were then analyzed for nodal involvement.The overall sensitivity, specificity, an...Continue Reading

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Citations

Sep 30, 2021·World Journal of Surgical Oncology·Isabela Panzeri Carlotti BuzattoDaniel Guimarães Tiezzi

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Methods Mentioned

BETA
biopsy
biopsies
dissection

Software Mentioned

SPSS
Excel

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