Is "prepectoral edema" a morphologic sign for malignant breast tumors?

Academic Radiology
Clemens KaiserKlaus Wasser

Abstract

A variety of morphologic and kinetic signs of benign or malignant breast lesions contribute to a final diagnosis and differential diagnosis in magnetic resonance (MR) mammography (MRM). As a new sign, prepectoral edema (PE) in patients without any history of previous biopsy, operation, radiation, or chemotherapy was detected during routine breast MR examinations. The purpose of this study was to retrospectively evaluate the role of this morphologic sign in the differential diagnosis of breast lesions. Between January 2005 and October 2006, a total of 1109 consecutive MRM examinations have been performed in our institution. In this study, only patients who would later be biopsied or operated in our own hospital were included. They had no previous operation, biopsy, intervention, chemotherapy, hormone replacement therapy, or previous mastitis. In total, 162 patients with 180 lesions were included, histologically correlated later-on by open biopsy (124 patients and 136 lesions) or core biopsy (38 patients and 44 lesions). The evaluations were performed by four experienced radiologists in consensus. One hundred eighty evaluated lesions included 104 malignant lesions (93 invasive and 11 noninvasive cancers) and 76 benign lesions. PE...Continue Reading

References

Sep 8, 1989·Deutsche medizinische Wochenschrift·W A Kaiser
Nov 18, 1971·The New England Journal of Medicine·J Folkman
Jan 1, 1996·Journal of Computer Assisted Tomography·R GillesR Arriagada
Apr 7, 2000·The American Journal of Pathology·H HashizumeD M McDonald
Jun 30, 2000·RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin·U Bick
Sep 28, 2002·International Immunopharmacology·Antonio SicaAlberto Mantovani
Dec 1, 2009·Journal of the American College of Radiology : JACR·Elizabeth S BurnsideCarl J D'Orsi
Apr 13, 2011·European Journal of Radiology·P A T BaltzerW A Kaiser

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