PMID: 9179073Jun 1, 1997Paper

Is primitive neuroectodermal tumor of the kidney a distinct entity?

Cancer
C Rodriguez-GalindoW H Meyer

Abstract

Primitive neuroectodermal tumors (PNETs) constitute a family of neoplasms of presumed neuroectodermal origin, most often presenting as bone or soft tissue masses in the trunk or axial skeleton in adolescents and young adults. As a soft tissue neoplasm, PNET arising in the kidney has not been well described, with only three cases previously reported. Four patients with PNET of the kidney were diagnosed and treated at St. Jude Children's Research Hospital. The authors reviewed the clinical, radiologic, and pathologic features and outcomes of these cases and of those previously described. The authors' patients were age 4-20 years. They presented with unilateral renal masses and metastatic disease in the lymph nodes (three patients), lungs (three patients), bone (two patients), liver (one patient), and bone marrow (one patient). Treatment included surgery, radiotherapy, and multiagent chemotherapy. Three of the patients died of progressive disease within 14 months of diagnosis. Features and outcomes were similar to those of the three previously reported cases. PNET of the kidney appears to be a distinct entity. Although rare, it must be included in the differential diagnosis of renal tumors in children and young adults. Patients us...Continue Reading

Citations

Feb 19, 2004·BMC Cancer·Giorgio PomaraCesare Selli
Dec 21, 2000·Pathology International·M KurodaM Kasahara
Oct 30, 2009·Pediatric Hematology and Oncology·Elvan Caglar CitakNalan Akyurek
Dec 23, 2006·Journal of the Formosan Medical Association = Taiwan Yi Zhi·Kuo-How HuangJun Chen
Jul 13, 2012·Urology·Arianna TagarelliGianni Bisogno
Aug 31, 2010·Actas urologicas españolas·F Cabrera-MeirásO Leiva-Galvis
Mar 1, 2008·Urology·Yuvaraja B ThyavihallySangita B Desai
Apr 26, 2005·Clinics in Laboratory Medicine·Gregory T MacLennan, David G Bostwick
Dec 13, 2006·Pediatric Blood & Cancer·Malcolm A SmithPeter J Houghton
Feb 11, 2015·Cell Biochemistry and Biophysics·Junqiang DongJianbo Gao
Jun 17, 2015·Journal of the Egyptian National Cancer Institute·Prashanth GiridharPramod Kumar Julka

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