Is Screening for Chlamydia and Gonorrhea in Men Who Have Sex With Men Associated With Reduction of the Prevalence of these Infections? A Systematic Review of Observational Studies

Sexually Transmitted Diseases
Achilleas TsoumanisChris Richard Kenyon

Abstract

Neisseria gonorrhoeae (gonorrhea) could become untreatable in the near future. Indeed, while the treatment of symptomatic gonorrhea in core groups, such men who have sex with men (MSM), is crucial for gonorrhea control programs, screening for and treating asymptomatic gonorrhea/Chlamydia trachomatis(chlamydia) in MSM may contribute to antibiotic resistance in gonorrhea. In this systematic review, we aim to assess if there is evidence that screening MSM for gonorrhea/chlamydia is associated with a decline in the prevalence of these infections. We conducted a systematic review in PubMed and Web of Science for relevant studies including uncontrolled observational studies and reported the results following the PRISMA guidelines. The change in estimated prevalences for chlamydia and gonorrhea across the different time points for 3 anatomical sites (oral, urethral and anal) were collected and examined. Twelve studies met our entry criteria. We were able to statistically assess the change in prevalence in 10 of 12 studies. In 3 studies, there was a significant increase in chlamydia prevalence, whereas for gonorrhea, 2 studies reported a significant increase and 2 others a decrease. Our review provides little evidence that screening fo...Continue Reading

References

Oct 20, 2006·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Sheldon R MorrisGrant N Colfax
Nov 26, 2010·The New England Journal of Medicine·Robert M GrantUNKNOWN iPrEx Study Team
Dec 16, 2011·Sexually Transmitted Infections·Christina H ChanDavid N Fisman
Sep 21, 2013·BMC Infectious Diseases·Maria XiridouMarianne A B van der Sande
Nov 21, 2013·The Lancet Infectious Diseases·Ramanan LaxminarayanOtto Cars
Feb 28, 2014·Future Microbiology·Paula Bianca BlomquistBambos M Charalambous
Sep 23, 2014·Annals of Internal Medicine·Bernadette ZakherHeidi D Nelson
Dec 2, 2015·The New England Journal of Medicine·Jean-Michel MolinaUNKNOWN ANRS IPERGAY Study Group
May 20, 2016·PLoS Pathogens·Stephanie M FingerhuthChristian L Althaus
Jul 16, 2016·MMWR. Surveillance Summaries : Morbidity and Mortality Weekly Report. Surveillance Summaries·Robert D KirkcaldyElizabeth Torrone
Aug 4, 2016·International Journal of STD & AIDS·Chris R KenyonMarc Vandenbruane

❮ Previous
Next ❯

Citations

Aug 31, 2019·Journal of the International AIDS Society·Teodora Ec WiMagnus Unemo
Feb 1, 2020·International Journal of STD & AIDS·Miguel Fernández-HuertaMateu Espasa
Jun 23, 2020·The European Journal of Contraception & Reproductive Health Care : the Official Journal of the European Society of Contraception·Jack BurtonTom Nadarzynski
Jun 26, 2020·MMW Fortschritte der Medizin·Petra Spornraft-Ragaller
Sep 10, 2020·International Journal of STD & AIDS·Chris KenyonKristien Wouters
Dec 30, 2018·BMJ Case Reports·Courtney L HanlonRandall S Edson
Jun 30, 2019·Frontiers in Public Health·Chris Kenyon
Sep 27, 2019·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Geneviève A F S van LiereChristian J P A Hoebe
Jun 19, 2021·International Journal of STD & AIDS·Thibaut VanbaelenChris Kenyon
Jun 25, 2021·PloS One·Eric FarfourUNKNOWN DRIVER study group
Oct 14, 2021·Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz·Ulrich Marcus, Susanne B Schink
Jan 5, 2022·International Journal of STD & AIDS·Chris KenyonChristophe Van Dijck

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.