PMID: 3944978Feb 14, 1986Paper

Is serum creatine kinase-MB in electrically injured patients predictive of myocardial injury?

JAMA : the Journal of the American Medical Association
J W McBrideI F Goldenberg

Abstract

We undertook a retrospective study of 36 victims of high-voltage electrical contact injuries to determine the incidence and possible source of elevated creatine kinase (CK)-MB enzyme in their serum. Only two sustained myocardial infarctions (one late) according to history, electrocardiographic findings, and clinical course. Serum lactate dehydrogenase isoenzyme levels were abnormal but revealed no myocardial infarction patterns. Creatine kinase total activity, however, reached 1.5 to 1,140 times normal in 92% and the CK-MB level was abnormal in 50% despite the low incidence of myocardial damage. Skeletal muscle CK and CK-MB levels in four nonelectrically injured patients were comparable to those in normal muscle while CK and CK-MB activity was elevated in six such electrical injuries. There was a gradient in CK-MB activity with greatest CK-MB activity in "normal" muscle near the injury site, lesser amounts in border tissue, and least in the worst-injured site. We conclude that myocardial injury is uncommon in high-voltage electrical injury and skeletal muscle injured by high electrical voltage is stimulated to produce, as well as release, CK-MB.

Citations

Nov 10, 2004·The Journal of Burn Care & Rehabilitation·Brett D ArnoldoJohn L Hunt
May 29, 2012·The American Journal of Emergency Medicine·Hakan AkilliHasan Gok
Sep 1, 1989·The Journal of Emergency Medicine·D T StuelandD A Cleveland
May 1, 1995·Annals of Emergency Medicine·B BaileyJ P Turgeon
Feb 1, 1993·Annals of Emergency Medicine·P B Fontanarosa
Apr 27, 2017·European Heart Journal·Victor WaldmannEloi Marijon

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