Is smaller worse? New insights about associations of PM1 and respiratory health in children and adolescents

Environment International
Mo YangGuang-Hui Dong

Abstract

Little is known about PM1 effects on respiratory health, relative to larger size fractions (PM2.5). To address this literature gap, we assessed associations between PM1 exposure and asthmatic symptoms in Chinese children and adolescents, compared with PM2.5. A total of 59,754 children, aged 2-17 years, were recruited from 94 kindergartens, elementary and middle schools in the Seven Northeast Cities (SNEC) study, during 2012-2013. We obtained information on asthma and asthma-related symptoms including wheeze, persistent phlegm, and persistent cough using a standardized questionnaire developed by the American Thoracic Society. PM1 and PM2.5 concentrations were estimated using a spatial statistical model matched to the children's geocoded home addresses. To examine the associations, mixed models with school/kindergarten as random intercept were used, controlling for covariates. Odds ratios (ORs) of doctor-diagnosed asthma associated with a 10-μg/m3 increase for PM1 and PM2.5 were 1.56 (95% CI: 1.46-1.66) and 1.50 (1.41-1.59), respectively, and similar pattern were observed for other outcomes. Interaction analyses indicated that boys and the individuals with an allergic predisposition may be vulnerable subgroups. For example, among...Continue Reading

Citations

Nov 15, 2019·Current Opinion in Pulmonary Medicine·Annelies BontinckGuy Joos
Dec 19, 2019·Frontiers in Pediatrics·Yu ZhuJinzhun Wu
Jul 17, 2020·Archives of Environmental Contamination and Toxicology·Jinjin WangChengjiang Zhang
Jul 6, 2019·Frontiers in Pediatrics·Shyamali C DharmageAdnan Custovic
Jan 6, 2021·International Journal of Environmental Research and Public Health·Sarah CommodoreKelly J Hunt
Jul 24, 2020·Environment International·Xiao-Wen ZengGuang-Hui Dong
Feb 25, 2021·Journal of the Air & Waste Management Association·Mahmoud M M Abdel-Salam
Mar 9, 2021·The Journal of Allergy and Clinical Immunology·Yunquan ZhangLing Zhang
Oct 11, 2021·Environmental Science and Pollution Research International·Yaoyu HuXiangtong Liu

❮ Previous
Next ❯

Related Concepts

Related Feeds

Asthma

This feed focuses in Asthma in which your airways narrow and swell. This can make breathing difficult and trigger coughing, wheezing and shortness of breath.

Allergies & Environmental Factors

Environmental factors are strongly associated with the prevalence of allergies and are an increasing health concern worldwide. Discover the latest research on Allergies and Environmental Factors here.

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.