Is squatting a triggering factor for stroke in Indians?

Acta Neurologica Scandinavica
S D ChakrabartiA Chakravarty

Abstract

Undocumented observations of ours suggested increased occurrence of strokes in the early hours of the morning and in the toilets where most Indians still squat. The present study has been designed to assess the validity of this observation and to identify the likely triggering factor in stroke onset in such situations. Part A of the study looked into stroke onset data of 100 consecutive CT-confirmed stroke patients specially in relation to time of day, place, posture and activity of the individual. Part B of the study included 67 healthy volunteers (age 24-49 years) whose supine and squatting blood pressure (BP) were measured and the differences noted. Part C of the study consisted of repeating the same procedure in 104 known hypertensives on treatment (age 28-60 years). Part A of the study revealed that most strokes (52%) occurred in the morning and at home (86%) and over a third (36%) while in toilets. Thirty-six per cent of the strokes occurred while the subjects squatted, mostly during the act of defecation. More than half of the haemorrhagic strokes occurred while the subjects were in squatting position. In normal healthy volunteers squatting produced a small (8.09 +/- 7.04 mmHg) but significant rise in systolic blood pres...Continue Reading

References

Apr 15, 1978·Lancet·M W Millar-CraigE B Raftery
Oct 3, 1991·The New England Journal of Medicine·J A PanzaA A Quyyumi
Apr 1, 1989·Stroke; a Journal of Cerebral Circulation·J R MarlerM A Foulkes
Dec 1, 1985·Neurosurgery·S A TsementzisD G Beevers
Apr 1, 1993·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·A D ten HarkelW Wieling

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Citations

Sep 19, 2003·Medical Hypotheses·A Chakravarty
Nov 12, 2005·BMJ : British Medical Journal·Raj BhopalAziz Sheikh
May 4, 2010·Annals of Indian Academy of Neurology·Nishant K Mishra, Satish V Khadilkar
Feb 12, 2014·Nature Reviews. Neurology·Mohammad WasaySubhash Kaul
May 12, 2007·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Jeyaraj Durai PandianStephen J Read
Apr 17, 2007·Lancet Neurology·Saif S M Razvi, Srinivasan Srikanth
Nov 21, 2012·International Journal of Clinical Practice·M H PalmerJ-J Wyndaele
Apr 1, 2010·Lower Urinary Tract Symptoms·Ryuji SakakibaraTomonori Yamanishi
Apr 1, 2011·Autonomic Neuroscience : Basic & Clinical·Jean-Christophe Philips, André J Scheen
Jan 15, 2011·Stroke Research and Treatment·Manjari Tripathi, Deepti Vibha
Sep 1, 2017·Geriatrics & Gerontology International·Joji InamasuMasashi Nakatsukasa
Dec 22, 2006·Expert Review of Neurotherapeutics·Puneet KakarGregory Y H Lip
Mar 30, 2021·Techniques in Coloproctology·S-C ChenH Gregersen

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