Is the clinical outcome after cartilage treatment affected by subchondral bone edema?

Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA
Giuseppe FilardoMaurilio Marcacci

Abstract

Subchondral bone edema is a common finding after cartilage treatment, but its interpretation is still debated. The aim of this study is to analyse the presence of edema after matrix-assisted autologous chondrocyte transplantation (MACT) for knee cartilage lesions at different follow-up times and its correlation with the clinical outcome. Two hundred and forty-eight magnetic resonance imagings (MRIs) of patients treated with a hyaluronic acid-based MACT for lesions of the knee articular surface were considered. The MRIs belonged to 116 patients (mean age at surgery 28.6 ± 10.3 years, average defect size 2.4 ± 1.0 cm(2)), 57 affected by degenerative cartilage lesions, 27 traumatic and 32 were osteochondritis dissecans (OCD). MRI follow-up was performed from 6 to 108 months after treatment. Other than its presence or absence, the subchondral bone edema was evaluated using a 3-level grading considering extension and hyperintensity, and with the WORMS score edema classification. The IKDC subjective score was collected at the time of every MRI. An analysis of the entire MRI group showed that edema is not constantly present through the follow-up, but presents a particular and well-defined trend. Edema was present within the first 2 ye...Continue Reading

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Citations

Mar 7, 2014·Journal of Materials Science. Materials in Medicine·Elizaveta KonMaurilio Marcacci
Apr 15, 2016·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Elizaveta KonNogah Shabshin
Jul 11, 2016·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·G FilardoM Marcacci
May 4, 2017·EFORT Open Reviews·Maurilio MarcacciGiuseppe Filardo
Jul 28, 2020·Frontiers in Bioengineering and Biotechnology·Bingchuan LiuXiaozhong Qu
May 29, 2018·Journal of Materials Science. Materials in Medicine·Giuseppe FilardoElizaveta Kon
Dec 14, 2018·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Giuseppe FilardoDennis C Crawford
May 9, 2021·Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association·Hailey P HuddlestonAdam B Yanke

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