Is the collecting activity of regional pharmacovigilance centers influenced by regional demographic or health determinants?

Thérapie
Laurent LamPatrick Maison

Abstract

To compare the regional demographic and health indicators to the pharmacovigilance activity of the regional pharmacovigilance centers in terms of number of cases collected, responses to information requests and signal detection in 2015. The pharmacovigilance activity parameters (collected cases reports, information requests, reported serious cases) were expressed in regional proportions to population size and compared to regional demographic and health indicators (population, individuals aged 60 and over, individuals aged under 20, socio-professional categories, health facilities per capita, hospital beds [medicine, surgery and obstetrics] per capita, physicians and pharmacists per capita, mortality rate and drug consumption per capita) in 12 French metropolitan areas. The Spearman correlation between these two parameters was analyzed. The territorial distribution of all demographic and health indicators and pharmacovigilance activity indicators in proportion to population size was different between regions (P<0.001): individuals aged 60 and over, individuals aged under 20, socio-professional categories, health facilities per capita, hospital beds per capita, health professionals per capita, mortality rate, drug consumption per...Continue Reading

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Citations

Dec 21, 2019·European Journal of Clinical Pharmacology·Margaux LafaurieJean-Louis Montastruc
Mar 17, 2020·Thérapie·Claire de CanecaudeGeneviève Durrieu

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