PMID: 9555155Apr 29, 1998Paper

Is the detection of familial hypercholesterolemia in children indicated? Occasionally, yes

Nederlands tijdschrift voor geneeskunde
J A Gevers Leuven

Abstract

Searching for familial hypercholesterolaemia (FH) in children is useful only if efficacious treatment is to be administered shortly and if there are relatives with ischaemic heart disease at very early ages. In all other cases, the (psychological) drawbacks probably outweigh the doubtful benefit of early intervention. The search for the major homozygous form of FH begins with cholesterol assay in both parents, in the absence of FH in either of them, the above-named restrictions apply.

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