PMID: 9432362Jul 1, 1997Paper

Is the only good Helicobacter a dead Helicobacter?

Helicobacter
J J Misiewicz

Abstract

Vast numbers of therapeutic studies of various drug regimens used for the cure of H. pylori infection have been published. However, many of these studies have been uncontrolled, included small numbers of patients, were published only as abstracts, differed widely in dosage sizes, schedules and durations and were of insufficient statistical power to make meaningful statements concerning their efficacy. Furthermore, there are no clear or universally accepted guidelines for the treatment of H. pylori infection. Thus, there remains profound confusion among practitioners on whom and how to treat. To critically review the currently available management strategies for H. pylori infection. Review of the literature. Treatment of H. pylori requires the use of multiple drug regimens (triple therapy) which can be expensive and is often associated with side effects. Bad choice of treatments, poor patient counseling and compliance will lead to the emergence of resistant H. pylori strains. Resistance to H. pylori to metronidazole is already widespread and resistance to other antimicrobial agents is increasing. The resource/financial implications are not negligible. The introduction of kits that will enable the identification of pathogenic str...Continue Reading

Citations

Jul 17, 2004·São Paulo Medical Journal = Revista Paulista De Medicina·Patrick BellelisWilson Roberto Catapani
Apr 28, 2005·Chemotherapy·Carmelo Scarpignato, Iva Pelosini
Feb 25, 2006·Digestion·Antonio GasbarriniCarmelo Scarpignato

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