Is the ovarian preservation safe in young women with stages IB-IIA villoglandular adenocarcinoma of the uterine cervix?

Journal of Gynecologic Oncology
U Chul JuSeok Mo Kim

Abstract

Because villoglandular adenocarcinoma (VGA) of the uterine cervix has favorable features and outcomes, patients receive less radical surgery and young women preserve their ovaries. We aimed to evaluate the clinicopathological features and outcomes of VGA and to see if the ovarian preservation is safe in young women with VGA. We retrospectively reviewed medical records and identified patients with VGA, who had been treated and followed from January 2004 to December 2015. This study consisted of 17 patients with VGA, including 9 premenopausal women. International Federation of Gynecology and Obstetrics (FIGO) stage IB1 disease was found in 12 patients (70.6%), IA1 in 2, IA2 in 1, IB2 in 1, and IIA1 in 1. Of the 12 women diagnosed with stage IB1 disease, a young woman received only conization and she has not showed a recurrence. During a median follow-up of 58 months (range: 12-116), 4 patients, who had undergone radical surgery for stage IB1 disease, had a recurrence and one of them died due to disease progression. Among patients with stages IB-IIA disease, 2 premenopausal women did not receive simultaneous oophorectomy or chemoradiation therapy. Both of them had a recurrent tumor at adnexa. This study revealed favorable features...Continue Reading

References

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Citations

Feb 21, 2021·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Jia-Hua ChenChunlin Chen
Mar 16, 2021·Best Practice & Research. Clinical Obstetrics & Gynaecology·Alexandros LaiosThomas Ind
May 27, 2021·Archives of Gynecology and Obstetrics·Anna K DietlKonrad Aumann

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Methods Mentioned

BETA
hysterectomy
dissection
Chip
biopsy
biopsies
genotyping

Software Mentioned

Statistical Package Service Solution ( SPSS )

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