Is the process of delivery of an individually tailored lifestyle intervention associated with improvements in LDL cholesterol and multiple lifestyle behaviours in people with familial hypercholesterolemia?

BMC Public Health
Karen BroekhuizenWillem van Mechelen

Abstract

More insight in the association between reach, dose and fidelity of intervention components and effects is needed. In the current study, we aimed to evaluate reach, dose and fidelity of an individually tailored lifestyle intervention in people with Familial Hypercholesterolemia (FH) and the association between intervention dose and changes in LDL-Cholesterol (LDL-C), and multiple lifestyle behaviours at 12-months follow-up. Participants (n = 181) randomly allocated to the intervention group received the PRO-FIT intervention consisting of computer-tailored lifestyle advice (PRO-FIT*advice) and counselling (face-to-face and telephone booster calls) using Motivational Interviewing (MI). According to a process evaluation plan, intervention reach, dose delivered and received, and MI fidelity were assessed using the recruitment database, website/counselling logs and the Motivational Interviewing Treatment Integrity (MITI 3.1.1.) code. Regression analyses were conducted to explore differences between participant and non-participant characteristics, and the association between intervention dose and change in LDL-C, and multiple lifestyle behaviours. A 34% (n = 181) representative proportion of the intended intervention group was reache...Continue Reading

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Citations

Mar 19, 2014·Journal of Clinical Lipidology·Gerald F WattsJohn J P Kastelein
May 13, 2015·Contemporary Clinical Trials·Judith G M JelsmaLars Forsberg
Jan 29, 2014·Contemporary Clinical Trials·William R Miller, Stephen Rollnick
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Dec 11, 2019·Atherosclerosis. Supplements·Viktoria KornevaUlrich Julius

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Software Mentioned

AIM
PRO
MITI
FIT
Motivational Interviewing Treatment Integrity code ( MITI
GezondLevenCheck
RE

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