Is the risk of childhood leukaemia associated with socioeconomic measures in Denmark? A nationwide register-based case-control study.

International Journal of Cancer. Journal International Du Cancer
Friederike ErdmannOle Raaschou-Nielsen

Abstract

The aetiology of childhood leukaemia is poorly understood. Knowledge about differences in risk by socioeconomic status (SES) may enhance etiologic insights. We conducted a nationwide register-based case-control study to evaluate socioeconomic differences in the risk of childhood leukaemia in Denmark and to access whether associations varied by different measures of SES, time point of assessment, leukaemia type and age at diagnosis. We identified all cases of leukaemia in children aged 0 to 19 years, born and diagnosed between 1980 and 2013 from the Danish Cancer Registry (N = 1336) and sampled four individually matched controls per case (N = 5330). We used conditional logistic regression models for analysis. Medium and high level of parental education was associated with a higher risk of acute myeloid leukaemia (AML) in the offspring, mainly driven by children diagnosed at ages 0 to 4 years [odds ratio (OR) for high maternal education = 3.07; 95% confidence interval (CI): 1.44-6.55]. We also observed a modestly increased risk for lymphoid leukaemia (LL) in association with higher level of parental education, but only in children diagnosed at ages 5 to 19 years. Higher parental income was associated with an increased risk of LL ...Continue Reading

References

Nov 15, 1987·International Journal of Cancer. Journal International Du Cancer·J M Birch, H B Marsden
Jan 1, 1997·Annual Review of Public Health·N KriegerN E Moss
Sep 10, 1999·International Journal of Epidemiology·J SchüzJ Michaelis
Feb 28, 2001·American Journal of Epidemiology·O Raaschou-NielsenJ H Olsen
Sep 17, 2004·Scandinavian Journal of Public Health·Ole Raaschou-NielsenJohnni Hansen
Feb 15, 2005·Early Human Development·Mel Greaves
Feb 16, 2005·Cancer·Eva Steliarova-FoucherPeter Kaatsch
Apr 26, 2005·BMJ : British Medical Journal·C GilhamUNKNOWN UKCCS Investigators
Jun 14, 2005·Epidemiology·Marilyn J BorugianMary L McBride
Dec 20, 2005·Journal of Epidemiology and Community Health·Bruna GalobardesGeorge Davey Smith
Feb 10, 2006·Nature Reviews. Cancer·Mel Greaves
Aug 9, 2008·International Journal of Cancer. Journal International Du Cancer·Karina Braga RibeiroCatherine Metayer
Oct 18, 2008·Radiation Protection Dosimetry·Martin AdamClaudia E Kuehni
Jan 29, 2009·International Journal of Cancer. Journal International Du Cancer·Robert W Caughey, Karin B Michels
Mar 4, 2010·Cancer Causes & Control : CCC·I-Jen PanKangmin Zhu
Aug 18, 2010·International Journal of Cancer. Journal International Du Cancer·Julie Von BehrenPeggy Reynolds
Sep 30, 2010·British Journal of Cancer·L KheifetsV Wunsch Filho
Mar 23, 2011·Pediatric Blood & Cancer·Danny R YouldenJoanne F Aitken
Aug 4, 2011·Scandinavian Journal of Public Health·Carsten Bøcker Pedersen
Aug 4, 2011·Scandinavian Journal of Public Health·Marianne Lundkjær Gjerstorff
Aug 4, 2011·Scandinavian Journal of Public Health·Vibeke M Jensen, Astrid W Rasmussen
Aug 4, 2011·Scandinavian Journal of Public Health·Mikkel Baadsgaard, Jarl Quitzau
Apr 5, 2014·International Journal of Cancer. Journal International Du Cancer·Helen D BaileyJoachim Schüz
Dec 2, 2014·Pediatric Clinics of North America·Logan G SpectorErin L Marcotte
Jun 20, 2015·Scandinavian Journal of Public Health·Ruby Del Risco KollerudBjørgulf Claussen
Jul 16, 2015·Frontiers in Oncology·Martin AdamMarcel Zwahlen
Aug 25, 2016·Paediatric and Perinatal Epidemiology·Fabienne MarquantJacqueline Clavel
Apr 6, 2017·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·Maria A KaralexiEleni Th Petridou
Aug 13, 2017·Environment International·Ben Daniel SpycherUNKNOWN Swiss National Cohort Study Group
Oct 17, 2017·American Journal of Epidemiology·Rebecca D KehmTheresa L Osypuk
Jan 20, 2018·European Journal of Epidemiology·Mette BliddalJens Langhoff-Roos
Apr 11, 2018·International Journal of Cancer. Journal International Du Cancer·Ole Raaschou-NielsenMette Sørensen
Apr 25, 2019·Environmental Health Perspectives·Tommaso FilippiniMarco Vinceti
Jul 14, 2019·The Journal of Pediatrics·Alicia G KachmarMartha A Q Curley

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