Is there a need for routine post-operative hemoglobin level estimation in total knee arthroplasty with tranexamic acid use?

The Knee
Navendu GoyalSamuel J MacDessi

Abstract

Total knee arthroplasty (TKA) can result in significant blood loss, leading to a need for blood transfusion. The major indication of transfusion is post-operative hemoglobin (Hb) levels in association with symptomatic anemia. The aim of this study was to determine the possibility of eliminating routine post-operative Hb tests in patients undergoing TKA with intra-articular tranexamic acid (TXA) use based on the predictability of pre-operative factors. We conducted a retrospective analysis of 487 patients who underwent TKA with intra-articular TXA use. Statistical analysis was done to predict the transfusion risk based on multiple pre-operative parameters. Post-operative blood transfusions were required in 2.5% of all patients. Pre-operative-Hb was the only significant predictor of post-operative transfusion (p<0.0001). Age, sex, weight, height and body mass index (BMI) were not related to post-operative transfusion risk. Transfusions were needed in 4.2% of patients with pre-operative Hb levels <14 g/dl. No patient with a pre-operative Hb >14 g/dl required a transfusion (p<0.0001). Pre-operative Hb is a strong predictor of post-operative blood transfusion risk. Patients who receive TXA in TKA, with a pre-operative Hb >14 g/dl do...Continue Reading

References

Jan 1, 1997·Seminars in Thrombosis and Hemostasis·S OkamotoU Okamoto
Apr 7, 2004·The Journal of Arthroplasty·Matthew R BongPaul E Di Cesare
Sep 24, 2004·Anesthesia and Analgesia·Saifudin RashiqBarry A Finegan
Nov 2, 2005·The Journal of Bone and Joint Surgery. British Volume·Y KalairajahA J Spriggins
Oct 27, 2006·Anesthesiology·Paul ZuffereySerge Molliex
Dec 14, 2011·The Journal of Bone and Joint Surgery. British Volume·S AlshrydaJ M Mason
Oct 3, 2012·Orthopedics·Issaq AhmedPhilip Walmsley
May 2, 2013·European Journal of Orthopaedic Surgery & Traumatology : Orthopédie Traumatologie·Federica Vigna-TagliantiRoberto Russo
Jul 28, 2013·The Journal of Arthroplasty·Blake P GilletteRafael J Sierra
Sep 27, 2013·The Journal of Arthroplasty·George F ChimentoSheena Babin
Oct 8, 2013·The Journal of Arthroplasty·Julian GilbodyJ Roderick Davey
Jun 4, 2014·The Journal of Arthroplasty·Hiroyuki Yoshihara, Daisuke Yoneoka

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Citations

May 30, 2016·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Jared Ze Yang YehSeng Jin Yeo
Aug 9, 2017·Clinical Orthopaedics and Related Research·Mitchell R KlementThorsten M Seyler

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