PMID: 32521841Jun 12, 2020Paper

Is there a place for F18-FDG PET/CT in the diagnosis of primary breast cancer?

Journal of B.U.ON. : Official Journal of the Balkan Union of Oncology
Dragos Stefan MorariuDoina Piciu

Abstract

With the improvement of techniques and the update of diagnostic protocols in breast cancer, modern imaging proves to be effective in the diagnosis of this pathology, as well as in its prognosis. This study aimed to evaluate the effectiveness of these modern imaging techniques through a systematic assessment of the most recent studies. A PUBMED search, using certain key combinations ("breast cancer", "F18 FDG PET-CT", "MRI", "staging", "diagnosis") and some inclusion and exclusion criteria, yielded 24 articles published during 2014-2018. Using these 24 articles, the various statistical tests showed a significant difference between modern imaging techniques, with respect to prognosis (p<0.05), in close correlation with the immunohistochemical profile of the tumor. Modern imaging techniques (F18-FDG/PET-CT, F18-FDG/PET-MRI) were validated to formulate a better prognostic value than conventional imaging, presenting a sustainable higher sensitivity and specificity in evidencing the locoregional invasion and the recurrence of this pathology.

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
Tjeerd S AukemaRenato A Valdés Olmos
Clinical Nuclear Medicine
Rodrigo de Carvalho FlaminiMarcelo Buarque de Gusmão Funari
Nuclear Medicine Communications
Kuruva ManoharGurpreet Singh
© 2022 Meta ULC. All rights reserved