Is There a Preferred Incision Location for Nipple-Sparing Mastectomy? A Systematic Review and Meta-Analysis

Plastic and Reconstructive Surgery
David A DaarKaren T Lane

Abstract

The incidence of nipple-sparing mastectomy is rising, but no single incision type has been proven to be superior. This study systematically evaluated the rate and efficacy of various nipple-sparing mastectomy incision locations, focusing on nipple-areola complex necrosis and reconstructive method. A systematic literature review was performed according to the Preferred Reporting Items for Systematic Review and Meta-Analyses guidelines identifying studies on nipple-sparing mastectomy where incision type was described. Pooled descriptive statistics meta-analysis of overall (nipple-areola complex) necrosis rate and nipple-areola complex necrosis by incision type was performed. Fifty-one studies (9975 nipple-sparing mastectomies) were included. Thirty-two incision variations were identified and categorized into one of six groups: inframammary fold, radial, periareolar, mastopexy/prior scar/reduction, endoscopic, and other. The most common incision types were inframammary fold [3634 nipple-sparing mastectomies (37.8 percent)] and radial [3575 nipple-sparing mastectomies (37.2 percent)]. Meta-analysis revealed an overall partial nipple-areola complex necrosis rate of 4.62 percent (95 percent CI, 3.14 to 6.37 percent) and a total nippl...Continue Reading

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Citations

Dec 29, 2020·Frontiers in Oncology·Pauline SimonGilles Houvenaeghel
May 4, 2020·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Bo Young ParkKyong-Je Woo
Dec 29, 2020·Plastic and Reconstructive Surgery·Edward I Chang
Feb 22, 2021·The Breast : Official Journal of the European Society of Mastology·Orit Kaidar-PersonPhilip Poortmans
Jun 29, 2021·Plastic and Reconstructive Surgery·Elisa ViciniViviana Galimberti
Jul 23, 2021·Annals of Surgical Oncology·Tammy JuIrene Wapnir
Nov 9, 2021·Annals of Surgical Oncology·Antonio J EsguevaUNKNOWN INSPIRE collaborators group
Nov 2, 2021·Breast Care·Francisco Pimentel Cavalcante
Jan 26, 2022·Plastic and Reconstructive Surgery·Ruth TevlinArash Momeni

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