Is there a right hemi-hyper-dopaminergic psychosis?

Schizophrenia Research
H S Bracha

Abstract

This selective review argues that a small subgroup among the patients meeting DSM-III-R criteria for schizophrenia appears to have an underlying right striatal hyper-dopaminergia. The subgroup is distinguished by a group of objective signs including: (1) asymmetric, usually right-sided, neuroleptic induced parkinsonian side effects; (2) asymmetric, usually left-sided, tardive dyskinesia; (3) a subclinical tendency to turn toward the left; (4) a subclinical right hemi-space sensory neglect; and (5) dopamine receptor densities greater in the right striatum than in the left.

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