Is There a Role for the Non-Helicobacter pylori Bacteria in the Risk of Developing Gastric Cancer?

International Journal of Molecular Sciences
Jackie Li, Guillermo I Perez Perez

Abstract

Helicobacter pylori is the most abundant bacterium in the gastric epithelium, and its presence has been associated with the risk of developing gastric cancer. As of 15 years ago, no other bacteria were associated with gastric epithelial colonization; but thanks to new methodologies, many other non-H. pylori bacteria have been identified. It is possible that non-H. pylori may have a significant role in the development of gastric cancer. Here, we discuss the specific role of H. pylori as a potential trigger for events that may be conducive to gastric cancer, and consider whether or not the rest of the gastric microbiota represent an additional risk in the development of this disease.

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Citations

Oct 14, 2018·International Journal of Molecular Sciences·Valli De Re
Mar 7, 2020·Alimentary Pharmacology & Therapeutics·Boldbaatar GantuyaYoshio Yamaoka
Feb 19, 2019·Helicobacter·Massimo RuggeAntonio Giuseppe Naccarato
Mar 27, 2021·Cellular Oncology (Dordrecht)·Yilin DengHui Li
Jun 3, 2021·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·Qing LiHonggang Yu

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Methods Mentioned

BETA
transgenic
biopsy
biopsies

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