Is there any association between prostate-specific antigen screening frequency and uptake of active surveillance in men with low or very low risk prostate cancer?

BMC Urology
Kerri BeckmannMieke Van Hemelrijck

Abstract

Patient-related factors such as concern about cancer are believed to influence both men's decisions to undergo prostate specific antigen (PSA) testing and to have definitive treatment if diagnosed with low risk prostate cancer (PCa). The potential link between screening frequency and choice of active surveillance (AS) for low risk disease has not been studied previously. Our aim was to investigate whether there is any association between PCa screening frequency or previous negative prostate biopsy and uptake of AS among men with low risk PCa. This register-based study included all men ≤75 years from Stockholm who were diagnosed with low risk PCa from 2008 to 2014 (n = 4336). Pre-diagnostic PSA testing and biopsy histories were obtained from the Stockholm PSA and Biopsy Register, a population-based register for the Stockholm country. The association between previous screening/biopsy history and AS uptake (based on primary treatment recorded in the National Prostate Cancer Register) was examined using multivariable logistic regression. Forty seven percent of men with low risk PCa underwent AS. Uptake was associated with older age, very low risk disease, more recent diagnosis and absence of family history. None of the screening/bi...Continue Reading

References

Feb 24, 2006·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Nathan S ConsedineAlfred I Neugut
Dec 23, 2008·Molecular Nutrition & Food Research·Peter D BaadeLauren J Krnjacki
Apr 8, 2010·British Journal of Cancer·R C MacefieldUNKNOWN ProtecT Study Group
Feb 24, 2012·Current Opinion in Urology·Roderick C N van den BerghChris H Bangma
Jun 16, 2012·European Urology·Marc A Dall'EraMark S Soloway
Oct 23, 2013·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Julia WadeJenny L Donovan
Mar 29, 2014·Current Opinion in Urology·Jonas Hugosson, Sigrid Carlsson
Dec 4, 2014·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Katarina TomicPär Stattin
Feb 19, 2015·Current Opinion in Urology·Peter C Albertsen
Feb 19, 2015·Current Opinion in Urology·Marc A Dall'Era
May 29, 2015·Current Urology Reports·Michele FascelliPeter A Pinto
Jul 8, 2015·JAMA : the Journal of the American Medical Association·Matthew R Cooperberg, Peter R Carroll
Oct 22, 2016·JAMA Oncology·Stacy LoebPär Stattin
Nov 2, 2016·Canadian Urological Association Journal = Journal De L'Association Des Urologues Du Canada·Patrick O RichardAntonio Finelli
Mar 8, 2017·Current Opinion in Urology·Laurence Klotz

❮ Previous
Next ❯

Methods Mentioned

BETA
biopsy
biopsies

Related Concepts

Related Feeds

Cardiovascular Diseases: Risk Factors

Cardiovascular disease is a significant health concern. Risk factors include hypertension, obesity, dyslipidemia and smoking. Women who are postmenopausal are at an increased risk of heart disease. Here is the latest research for risk factors of cardiovascular disease.

Cardiovascular Risk Prediction

Cardiovascular risk prediction models based on classical risk factors identified in epidemiological studies are useful in primary prevention of cardiovascular disease in individuals. Here is the latest research.

Related Papers

European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)
Tobias NordströmHenrik Grönberg
European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)
Rhiannon C MacefieldJ L Donovan
American Journal of Men's Health
Caitlin BiddleHeather Orom
© 2021 Meta ULC. All rights reserved