Is There Any Potential of FDG PET/CT in Monitoring Disease Activity in Familial Hemophagocytic Lymphohistiocytosis?

Clinical Nuclear Medicine
YongXiang TangShuo Hu

Abstract

FDG PET/CT was performed in a 30-year-old woman to detect the source of fever of unknown origin. The images showed widespread abnormal activity, consistent with lymphoma. However, lymph node biopsy revealed only inflammation, and a diagnosis of familial hemophagocytic lymphohistiocytosis was eventually made after familial hemophagocytic lymphohistiocytosis-specific gene was detected. After proper therapy, a follow-up FDG PET/CT examination 2 months later showed resolution of most of the previously seen lesions.

References

Apr 21, 2004·Clinical Nuclear Medicine·Choong L Wong, Michael J Fulham
Aug 29, 2006·Pediatric Blood & Cancer·Jan-Inge HenterGritta Janka
Feb 9, 2010·Clinical Nuclear Medicine·Damita L ThomasMichael M Graham
Feb 7, 2015·European Journal of Nuclear Medicine and Molecular Imaging·H BalinkH J Verberne
Oct 16, 2015·Hematology/oncology Clinics of North America·Barbara Degar
Apr 1, 2012·PET Clinics·Jigang YangSabah Servaes
Jul 14, 2016·Indian Journal of Hematology & Blood Transfusion : an Official Journal of Indian Society of Hematology and Blood Transfusion·Prabhas Prasun GiriSwati Chakravarty
Aug 19, 2016·Diagnostic and Interventional Radiology : Official Journal of the Turkish Society of Radiology·Leilei YuanJigang Yang
Dec 30, 2016·Clinical Nuclear Medicine·W Phillip LawKenneth A Miles
Jun 8, 2017·Clinical Nuclear Medicine·W Phillip LawPeter Jackson
Dec 1, 2017·Clinical Nuclear Medicine·Yu Pan, Yifan Zhang

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Ryōikibetsu shōkōgun shirīzu
K TsunamotoS Imashuku
Journal of Perinatology : Official Journal of the California Perinatal Association
T E Herman, M J Siegel
[Rinshō ketsueki] The Japanese journal of clinical hematology
M Sako
Archives françaises de pédiatrie
E Majdalani, J Vassoyan
© 2022 Meta ULC. All rights reserved