Is there cardiac risk in panic disorder? An updated systematic review

Journal of Affective Disorders
Daniela CaldirolaGiampaolo Perna

Abstract

The recognized relationship between panic disorder (PD) and cardiac disorders (CDs) is not unequivocal. We reviewed the association between PD and coronary artery disease (CAD), arrhythmias, cardiomyopathies, and sudden cardiac death. We undertook an updated systematic review, according to PRISMA guidelines. Relevant studies dating from January 1, 2000, to December 31, 2014, were identified using the PubMed database and a review of bibliographies. The psychiatric and cardiac diagnostic methodology used in each study was then to very selective inclusion criteria. Of 3044 studies, 14 on CAD, 2 on cardiomyopathies, and 1 on arrhythmias were included. Overall, the studies supported a panic-CAD association. Furthermore, in some of the studies finding no association between current full-blown PD and CAD, a broader susceptibility to panic, manifesting as past PD, current agoraphobia, or subthreshold panic symptoms, appeared to be relevant to the development of CAD. Preliminary data indicated associations between panic, arrhythmias, and cardiomyopathies. The studies were largely cross-sectional and conducted in cardiological settings. Only a few included blind settings. The clinical conditions of patients with CDs and the qualification...Continue Reading

References

Oct 1, 1987·The American Journal of Psychiatry·J P KahnD F Klein
Mar 1, 1982·The American Journal of Cardiology·L A GirottiM B Rosenbaum
May 1, 1993·The American Journal of Psychiatry·J M ChignonJ Ades
Oct 6, 1997·Biological Psychiatry·G PernaL Bellodi
Aug 18, 1999·Journal of Consulting and Clinical Psychology·D M ClarkM Gelder
Apr 6, 2000·Pacing and Clinical Electrophysiology : PACE·P E DilaverisJ E Gialafos
Apr 13, 2000·Psychiatry Research·V K YeraganiK Srinivasan
Jul 6, 2000·Journal of Psychosomatic Research·R FleetB D Beitman
Jul 6, 2000·European Psychiatry : the Journal of the Association of European Psychiatrists·R HeunU Ptok
Oct 18, 2000·Journal of Psychosomatic Research·E J GriezJ B Bouhour
Apr 12, 2001·Biological Psychiatry·F H WilhelmW T Roth
Nov 1, 2001·Behaviour Research and Therapy·D W Austin, J C Richards
May 2, 2003·Psychosomatics·Jeff C Huffman, Mark H Pollack
Apr 15, 2004·The Journal of the American Board of Family Practice·David Katerndahl
Sep 24, 2004·Psychosomatic Medicine·Bettina BankierAndrew B Littman
Mar 15, 2005·American Journal of Respiratory and Critical Care Medicine·Gregor HaslerJules Angst
Oct 6, 2005·Psychosomatic Medicine·Andres Gomez-CamineroRuby Castilla-Puentes
Jan 13, 2006·Depression and Anxiety·Vladan Starcevic, David Berle
Jul 18, 2006·Psychosomatics·Chiara RafanelliYuri Milaneschi
May 1, 2007·Journal of Affective Disorders·Neeltje BatelaanAartjan Beekman
May 19, 2007·Psychosomatic Medicine·Mustafa YavuzkirI Nadi Aslan
Jun 15, 2007·Journal of Cardiopulmonary Rehabilitation and Prevention·John F TodaroRaymond Niaura
Jan 1, 2008·General Hospital Psychiatry·John F MorganMartin M Schmidt
Jan 9, 2008·Archives of General Psychiatry·Nancy Frasure-Smith, François Lespérance
Jan 23, 2009·Primary Care Companion to the Journal of Clinical Psychiatry·David A Katerndahl
Dec 8, 2009·The Journal of Clinical Psychiatry·Fiammetta CosciKoen R J Schruers
Jan 16, 2010·Journal of Applied Physiology·Patrice G GuyenetRoy Kanbar
Mar 27, 2010·Journal of the American College of Cardiology·Charalambos VlachopoulosChristodoulos Stefanadis
Mar 24, 2011·The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry·Sébastien GrenierUNKNOWN Scientific Committee of the ESA Study
Jul 26, 2011·Biological Psychiatry·Alicia E MeuretWalton T Roth

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