Is thromboelastography (TEG)-based resuscitation better than empirical 1:1 transfusion?

Trauma Surgery & Acute Care Open
Isaac W HowleyThomas M Scalea

Abstract

Thomboelastography (TEG) is a whole blood measure of coagulation which was originally described in the 1950s. However, it has only been in the last few decades that assays have become accessible and viable as a point-of-care test. Following the observation that hemorrhagic shock is associated with an intrinsic coagulopathy, TEG has been used as a method of diagnosing specific coagulation defects in order to direct individualized blood products resuscitation. An alternative transfusion strategy is the administration of fixed ratio products, a paradigm borne out of military experience. It is unknown which strategy is superior and this topic was debated at the 36th Annual Point/Counterpoint Acute Care Surgery Conference. The following article summarizes the discussants points of view along with a summary of the evidence. Level III.

Citations

Sep 11, 2018·Critical Care Medicine·Samuel A Tisherman, Deborah M Stein
Apr 17, 2019·Indian Journal of Hematology & Blood Transfusion : an Official Journal of Indian Society of Hematology and Blood Transfusion·Venencia AlbertSanjeev Kumar Bhoi
Jan 2, 2021·Practical Laboratory Medicine·Tapasyapreeti MukhopadhyayRenu Saxena
Feb 25, 2021·Journal of Thrombosis and Thrombolysis·Hui Yin LimPrahlad Ho
Dec 16, 2020·Practical Laboratory Medicine·Tapasyapreeti Mukhopadhyay, Arulselvi Subramanian
Sep 14, 2021·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Marie T KeithYekaterina Buriko

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