Is ultrasound a validated imaging tool for the diagnosis and management of synovitis in juvenile idiopathic arthritis? A systematic literature review

Arthritis Care & Research
Paz ColladoMaria Antonietta D'Agostino

Abstract

Ultrasound (US) has been shown to be a sensitive tool for evaluating synovitis in rheumatoid arthritis. However, the validity of US has not yet been established in juvenile idiopathic arthritis (JIA). The purpose of this study was to assess the validity of US for detecting synovitis for both diagnosis and followup in JIA. A systematic literature search in Embase and PubMed was performed before February 25, 2011. Selection criteria included original articles on children, JIA, US, Doppler, synovitis, and management published in the English language. Data were extracted from the articles meeting the inclusion criteria, particularly those focused on the US definition of synovitis, scoring systems used, and metric properties studied. The type and number of joints tested, study design, and quality of the studies were assessed. Twenty studies were identified using US to assess synovitis in JIA. The knee was the joint most commonly studied in these articles. There was heterogeneity regarding the US definition and quantification of synovitis. Synovitis was commonly assessed by using gray scale and only a few studies included the Doppler technique. Construct validity was reported in 80% of articles, including the clinical examination as ...Continue Reading

Citations

Mar 13, 2014·Current Rheumatology Reports·Stefano LanniClara Malattia
Dec 10, 2013·Rheumatology International·Vanessa Bugni Miotto e SilvaMaria Teresa Terreri
Jul 9, 2013·Radiologic Clinics of North America·Ricardo RestrepoPaul S Babyn
May 31, 2013·Rheumatic Diseases Clinics of North America·Sam R DalviJonathan Samuels
Dec 5, 2013·Journal of Clinical Ultrasound : JCU·Yuanjiao TangLi Qiu
Jul 23, 2014·Arthritis Care & Research·Johannes RothPaz Collado
Apr 24, 2015·Insights Into Imaging·Lil-Sofie Ording MullerKaren Rosendahl
Apr 10, 2014·Arthritis Research & Therapy·Kei IkedaHiroshi Nakajima
Jul 13, 2016·Rheumatology International·Daniel WindschallUNKNOWN Imaging Working Group of the German Society of Rheumatology in Childhood and Adolescense (GKJR)
Jul 29, 2015·Arthritis Care & Research·Paz ColladoUNKNOWN Omeract Ultrasound Pediatric Group
Oct 18, 2016·Arthritis Care & Research·Johannes RothUNKNOWN OMERACT Ultrasound Group
Feb 6, 2017·The Journal of Rheumatology·Lene TerslevUNKNOWN OMERACT Ultrasound Group
Nov 19, 2013·The Journal of Rheumatology·Annamaria IagnoccoMaria-Antonietta D'Agostino
Sep 8, 2018·Arthritis Care & Research·Tracy V TingUNKNOWN Childhood Arthritis and Rheumatology Research Alliance Juvenile Idiopathic Arthritis Ultrasound Workgroup
Feb 16, 2020·Annals of the Rheumatic Diseases·Rolando CimazRoberto Caporali
Nov 11, 2018·Journal of Ultrasound·Luigi BarbutoGianfranco Vallone
Aug 5, 2017·Arthritis Care & Research·Daniel WindschallUNKNOWN Outcome Measures in Rheumatology Pediatric Ultrasound Subtask Force

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