Is undernutrition prognostic of infection complications in children undergoing surgery? A systematic review

The Journal of Hospital Infection
R HillB Carter

Abstract

Healthcare-associated infections are costly and are increasingly viewed as an indicator of the quality of care. Although strategies to reduce infections have become widespread, few studies have formally investigated the role of undernutrition on the development of infection-related complications in children after surgery. To perform a systematic review of the literature to determine if undernutrition is prognostic of postoperative infection complications in children. Electronic bibliographic and research databases were searched from 1950 to 2014. Inclusion criteria were studies in children (age <18 years) evaluating pre-operative nutritional status and reporting postoperative infection complications. Quality assessment was performed independently by two reviewers, with disagreements resolved by a third reviewer. The quality of the evidence was judged to be low in the majority of studies. Ten cohort and two case-control studies met the inclusion criteria. Five studies reported an outcome combining infection-related complications, with the remainder reporting individual infection complications. Six studies reported surgical site infection (SSI) alone or in combination with other infection complications. Direct comparison between ...Continue Reading

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Citations

Mar 16, 2018·Antimicrobial Resistance and Infection Control·Nicholas AgyepongSabiha Yusuf Essack
Oct 19, 2020·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·C WallonA De Luca

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