Ischemic-like ST-segment changes during Holter monitoring in patients with angina pectoris and normal coronary arteries but negative exercise testing

The American Journal of Cardiology
G A LanzaA Maseri

Abstract

To evaluate whether Holter electrocardiographic monitoring may improve the detection of ST-segment depression in patients with anginal chest pain and normal coronary arteries, we performed symptom-limited exercise testing and 24-hour Holter monitoring in a group of 38 such patients (27 women, age 54 +/- 8 years). Patients were divided into 2 groups:group X1 included 28 patients with and group X2 10 patients without significant ST-segment depression during exercise testing. There were no significant differences between the 2 groups in age, gender, characteristics of chest pain, exercise duration, heart rate (HR), and blood pressure at peak exercise, but anginal pain during exercise testing was reported by 10 patients of group X1 (36%) and 9 of group X2 (90%) (p <0.01). Episodes of ST-segment depression on Holter monitoring were found in 17 patients of group X1 (61%) and in 5 patients of group X2 (50%) (p = NS). There were no differences between the 2 groups in daily number of ST episodes (3.6 +/- 4 vs 2.8 +/- 5 episodes per patient), symptomatic episodes (8% vs 18%), and duration of the episodes. On average, HR increased significantly, in a similar way, from 15 minutes before ST-segment depression to 1-mm ST in both groups, and ...Continue Reading

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Citations

Aug 6, 2014·Cardiology Clinics·Shilpa AgrawalC Noel Bairey Merz
Mar 13, 2012·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Peter OngJuan Carlos Kaski
Jan 9, 2007·European Journal of Nuclear Medicine and Molecular Imaging·Giovanni StortoAlberto Cuocolo
Mar 6, 2010·European Journal of Nuclear Medicine and Molecular Imaging·Alberto CuocoloAndrea Soricelli
Aug 19, 2000·The New England Journal of Medicine·E Bellin
Jan 13, 2005·Seminars in Nuclear Medicine·Josef Machac
Nov 17, 2015·Heart Failure Clinics·Shilpa AgrawalC Noel Bairey Merz
Jul 7, 2007·Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·E S ZegersA J M Oude Ophuis
Nov 22, 2000·American Journal of Physiology. Heart and Circulatory Physiology·A BuffonA Maseri

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