Ischemic Optic Neuropathy Following Spine Surgery: Case Control Analysis and Systematic Review of the Literature

Spine
Anshit GoyalMohamad Bydon

Abstract

Case-control analysis and systematic literature review. To illustrate the prognosis and perioperative risk factors associated with this condition. Ischemic optic neuropathy (ION) is the most common pathological diagnosis underlying postoperative vision loss. It comes in two primary forms-anterior (AION)-affecting the optic disc or posterior (PION) affecting the optic nerve proximal to the disc. Spine surgery remains one of the largest sources of acute perioperative visual loss. We performed a 1:4 case-control analysis (by age and year of surgery) for patients with ION and those who didn't develop ION following spine surgery at our institution. A systematic literature search of Medline, Embase, Scopus from inception to September 2017 as also performed. We identified 12 cases from our institution. Comparison to 48 matched controls revealed fusion, higher number of operative levels, blood loss, and change in hemoglobin, hematocrit to be significantly associated with ION. Majority were diagnosed with PION (83%, 10/12) and had bilateral presentation (75%, 9/12). Only 30% patients (3/10) demonstrated improvement in visual acuity while the rest remained either unchanged (40%, 4/10) or worsened (20%, 2/10) at last follow-up. Literature...Continue Reading

References

May 1, 1983·The Journal of Bone and Joint Surgery. British Volume·N A Malcolm-Smith, M J McMaster
Jul 1, 1994·Archives of Ophthalmology·D M KatzL B Kline
Jun 15, 1997·Spine·W R StevensD S Bradford
Oct 27, 1997·Journal of Neurosurgical Anesthesiology·S RothB D Schreider
Nov 13, 2001·American Journal of Ophthalmology·S R SaddaA Kouzis
Jun 26, 2002·Journal of the American College of Surgeons·Stephan DunkerAlfredo A Sadun
Dec 1, 1954·A.M.A. Archives of Ophthalmology·R W HOLLENHORSTC F BENOIT
Dec 29, 2004·Survey of Ophthalmology·Lawrence M Buono, Rod Foroozan
Mar 7, 2006·Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society·Jonathan W KimSimmons Lessell
Dec 10, 2008·Progress in Retinal and Eye Research·Sohan Singh Hayreh
Dec 22, 2011·Anesthesiology·UNKNOWN Postoperative Visual Loss Study Group
Nov 13, 2013·The Spine Journal : Official Journal of the North American Spine Society·Sreeharsha V NandyalaKern Singh
Apr 30, 2017·Global Spine Journal·Brandon C GabelK Daniel Riew

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Citations

Jan 24, 2020·Journal of Neurosurgical Anesthesiology·Jeffrey J Pasternak
Sep 29, 2020·Journal of Intensive Care Medicine·Priyanka SanghiBita Manzouri
Jan 20, 2021·BMJ Case Reports·Eswar RamakrishnanUvaraj R Nalli
Jul 3, 2021·Case Reports in Ophthalmological Medicine·Ahmed M HabibMahmood O Mekkawy
Jan 14, 2020·Journal of Neurosurgical Anesthesiology·Heung Kan Ma, John F Bebawy

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