PMID: 18196629Jan 16, 2008Paper

Ischemic stroke: hemostasis and factors of cerebral embolism

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova
Z A SuslinaV G Ionova

Abstract

Hemorheology and hemostasis in patients with ischemic stroke in comparison to the process of cerebral embolism are considered. Results of transcranial Doppler monitoring of microembolic signals and indices of coagulation and anticoagulation blood systems are analyzed. The changes of both hemorheology and hemostasis in ischemic disturbances of blood circulation are characterized by an increase of coagulation blood activity and suppression of anti-coagulation activity. In ischemic stroke, as compared to transitory ischemic attacks, the markers of thrombinemia were increased significantly that was most pronounced in cases of lacunar and cardioembolic genesis. Cerebral microembolism was associated with imbalance of hemostasis systems. The results of the study may be used in elaboration of recommendations for optimization of therapeutic arrangements in ischemic disturbances of cerebral blood circulation.

Related Concepts

Related Feeds

Acute Stroke

A stroke occurs when blood supply to the brain is interrupted depriving the brain of oxygen and nutrients. This feed focuses cerebrovascular accidents including ischemic and paralytic stroke.

Blood Clotting Disorders

Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.

Brain Ischemia

Brain ischemia is a condition in which there is insufficient blood flow to the brain to meet metabolic demand. Discover the latest research on brain ischemia here.