Islet amyloid polypeptide in pancreatic tissue of children with persistent hyperinsulinemic hypoglycemia caused by primary islet hyperplasia and nesidioblastosis

The Journal of Clinical Endocrinology and Metabolism
K I RotherP C Butler

Abstract

Islet amyloid is a recognized characteristic finding in insulinoma and secondary islet hyperplasia resulting from severe insulin resistance. Little information is available about the presence of islet amyloid in primary islet hyperplasia (nesidioblastosis) of childhood. Here we report that islet amyloid was not present in 12 children with primary islet hyperplasia associated with hyperinsulinemic hypoglycemia.

Citations

Aug 8, 2012·Journal of Indian Association of Pediatric Surgeons·Prabudh Goel, Subhasis Roy Choudhury

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