PMID: 8964599Jan 1, 1996Paper

Islet cell and glutamic acid decarboxylase antibodies and heat-shock protein 65 responses in children with newly diagnosed insulin-dependent diabetes mellitus

Immunology Letters
T ScheininS Kontiainen

Abstract

Islet cell antibodies (ICA) were detected in 66% and glutamic acid decarboxylase (GAD) antibodies in 64% of children (n = 47) with newly diagnosed insulin-dependent diabetes mellitus (IDDM). Fifteen percent of the patients had neither GAD nor ICA antibodies. Responses to mycobacterial heat-shock protein 65 (Hsp65) were detected in all patients. There was a significant correlation between anti-GAD antibodies and proliferation of peripheral blood mononuclear cells to Hsp65, and between ICA and antibodies to Hsp65.

References

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Citations

Jul 11, 2006·Medical Hypotheses·C Thomas Dow
Oct 20, 2019·Microorganisms·Coad Thomas Dow, Leonardo A Sechi
Mar 6, 2021·Journal of Translational Autoimmunity·Coad Thomas Dow, Edward D Chan

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