PMID: 6988264Jan 1, 1980Paper

Islet-cell antibodies and beta-cell function in insulin-dependent diabetics

Diabetologia
S MadsbadC Binder

Abstract

Residual insulin secretion and islet-cell antibodies were studied in 399 insulin-dependent diabetics with age at onset of between 10--19.9 years (248 patients) or 30--39.9 years (151 patients). We found the prevalence of islet-cell antibodies to be independent of residual beta-cell function as measured by serum C-peptide and age at onset. The cause and role of the persistence of islet-cell antibodies in insulin-dependent diabetics remain obscure.

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Related Concepts

C-Peptide
Diabetes Mellitus
Diabetes, Autoimmune
Islets of Langerhans

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