Isocyanates and work-related asthma: Findings from California, Massachusetts, Michigan, and New Jersey, 1993-2008

American Journal of Industrial Medicine
Daniel K LefkowitzKenneth D Rosenman

Abstract

Isocyanates remain a leading cause of work-related asthma (WRA). Two independent data systems were analyzed for the period 1993-2008: (1) State-based WRA case surveillance data on persons with isocyanate-induced WRA from four states, and (2) Occupational Safety and Health Administration (OSHA) Integrated Management Information System (IMIS) isocyanate air sampling results. We identified 368 cases of isocyanate-induced WRA from 32 industries and 678 OSHA isocyanate air samples with detectable levels from 31 industries. Seventeen industries were unique to one or the other dataset. Isocyanate-induced WRA continues to occur in a wide variety of industries. Two data systems uncovered industries with isocyanate exposures and/or illness. Improved control measures and standards, including medical surveillance, are needed. More emphasis is needed on task-specific guidance, spill clean-up procedures, skin and respiratory protection, and targeted medical monitoring to mitigate the hazards of isocyanate use.

References

Jun 1, 1992·The Journal of Allergy and Clinical Immunology·O VandenplasJ L Malo
Apr 1, 1990·British Journal of Industrial Medicine·J C LuoA Fischbein
May 1, 1997·Journal of Occupational and Environmental Medicine·K D RosenmanD J Kalinowski
May 8, 1998·Journal of Occupational and Environmental Medicine·J BiddleE M Welch
Mar 27, 1999·International Journal of Occupational and Environmental Health·P K HennebergerC A Geidenberger
Nov 15, 2000·Occupational and Environmental Medicine·S K MeredithR L Clark
Aug 29, 2002·American Journal of Public Health·Lenore S AzaroffDavid H Wegman
Oct 10, 2002·The Journal of Allergy and Clinical Immunology·Catherine LemièreJean-Luc Malo
May 24, 2003·Journal of Occupational and Environmental Medicine·Kenneth D RosenmanMargaret Filios
Sep 4, 2003·Environmental Health : a Global Access Science Source·Susan R SamaDonald K Milton
Jun 1, 1959·American Industrial Hygiene Association Journal·H T WALWORTH, W E VIRCHOW
Jul 1, 1962·American Industrial Hygiene Association Journal·H B ELKINSJ P FAHY
Feb 14, 1963·The New England Journal of Medicine·H G BRUGSCH, H B ELKINS
Jun 1, 1964·Archives of Environmental Health·E O LONGLEY
Oct 19, 2004·American Journal of Industrial Medicine·Dhimiter BelloCarrie A Redlich
Dec 14, 2004·Toxicological Sciences : an Official Journal of the Society of Toxicology·Joanna M MathesonMichael I Luster
May 14, 2005·Journal of Occupational and Environmental Medicine·David K BonautoDon J Lofgren
Jun 9, 2005·American Journal of Industrial Medicine·Debra A ChesterKenneth D Rosenman
Aug 30, 2005·The Annals of Occupational Hygiene·Anjoeka PronkLiesbeth Preller
Oct 20, 2005·Occupational and Environmental Medicine·D M WildA D Paltiel
Nov 15, 2006·Analytical and Bioanalytical Chemistry·Hartmut HennekenUwe Karst
Apr 14, 2007·Environmental Health Perspectives·Dhimiter BelloCarrie A Redlich
Nov 23, 2007·American Journal of Industrial Medicine·Jacek M MazurekRobert Harrison
Mar 1, 2008·Occupational Medicine·M S ShakeriJ G Ayres
Mar 5, 2008·Current Opinion in Allergy and Clinical Immunology·Carrie A Redlich, Christina A Herrick
Feb 5, 2009·Journal of Occupational and Environmental Hygiene·Karroll BoothJ Banta
Apr 30, 2010·Proceedings of the American Thoracic Society·Carrie A Redlich
Jun 16, 2010·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·A V Wisnewski, M Jones
Oct 19, 2010·Occupational and Environmental Medicine·Manon LabrecqueKhalil Rabhi
Jan 20, 2011·American Journal of Industrial Medicine·Scott A HennSangwoo Tak
Jan 22, 2011·The Annals of Occupational Hygiene·John Cocker
Feb 25, 2011·Journal of Occupational and Environmental Hygiene·Jennifer M ThomasenLeena A Nylander-French
Jul 9, 2011·Allergy, Asthma & Immunology Research·Olivier Vandenplas
Oct 12, 2011·American Journal of Industrial Medicine·Hille SuojalehtoKatri Suuronen
Mar 28, 2012·The Annals of Occupational Hygiene·Adam V WisnewskiCarrie A Redlich
Apr 17, 2012·Journal of Occupational and Environmental Hygiene·Carolyn Reeb-WhitakerLeena A Nylander-French
Jun 2, 2012·European Respiratory Review : an Official Journal of the European Respiratory Society·Dennis WilkenUNKNOWN ERS Task Force on the Management of Work-related Asthma
Jun 2, 2012·European Respiratory Review : an Official Journal of the European Respiratory Society·Dick HeederikUNKNOWN ERS Task Force on the Management of Work-related Asthma
Jun 2, 2012·European Respiratory Review : an Official Journal of the European Respiratory Society·Xaver BaurUNKNOWN ERS Task Force on the Management of Work-related Asthma
Jun 19, 2012·American Journal of Preventive Medicine·Jacek M Mazurek, Eileen Storey

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Citations

Nov 12, 2016·Chemosphere·María A GarridoJuan A Conesa
Jan 3, 2019·Current Opinion in Allergy and Clinical Immunology·Jacek M Mazurek, Paul K Henneberger
Nov 5, 2019·Annals of the American Thoracic Society·Mary Jo ReillyKenneth D Rosenman

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