Isoflavone Supplementation Does Not Potentiate the Effect of Combined Exercise Training on Resting and Ambulatory Blood Pressure in Non-Obese Postmenopausal Women: A Randomized Double-Blind Controlled Trial-A Pilot Study.

Nutrients
Juliene Gonçalves Costa DechichiGuilherme Morais Puga

Abstract

Physical exercise and isoflavone supplementation are potential strategies to prevent and treat cardiovascular diseases in postmenopausal women. The aim of this study was to investigate whether there are additive effects of isoflavone supplementation when associated with combined aerobic and resistance exercise on resting and ambulatory blood pressure monitoring (ABPM) and in blood pressure variability (BPV). Thirty-one non-obese postmenopausal women were randomly allocated into two groups: placebo and exercise (Placebo n = 19); and isoflavone supplementation (100 mg/day) and exercise (isoflavone n = 19). ABPM and BPV were evaluated before and after 10 weeks of moderate combined (aerobic and resistance) exercise training. Generalized Estimating Equation (GEE) with Bonferroni correction and intention-to-treat analysis was used to compare the effects of interventions on resting BP, ABPM and BPV. Combined exercise training decreased resting systolic (SBP) and diastolic blood pressure (DBP) and reduced 24 h and awake ambulatory SBP, DBP and mean blood pressure over time, with no additional effects of isoflavone supplementation. No changes were observed in sleep period, or in BPV indexes (Standard Deviation of 24 h (SD), daytime and ...Continue Reading

References

Feb 1, 1984·The American Review of Respiratory Disease·K Wasserman
Jan 1, 1997·Fertility and Sterility·E K HonoréT B Clarkson
Jan 23, 1998·Arteriosclerosis, Thrombosis, and Vascular Biology·P J NestelM Abbey
May 12, 1998·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·D O RuehlmannG E Mann
Oct 21, 2000·European Journal of Clinical Nutrition·B Beaufrère, B Morio
Jun 22, 2002·Clinical Physiology and Functional Imaging·Arja L T UusitaloRainer Rauramaa
Sep 13, 2002·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Shaw WatanabeYuriko Kikuchi
Feb 6, 2003·Medicine and Science in Sports and Exercise·Andrea C TaylorRonald L Wiley
Nov 6, 2003·Medicine and Science in Sports and Exercise·Pedro Curi HallalRosângela Costa Lima
Jan 17, 2004·American Journal of Physiology. Heart and Circulatory Physiology·Arja L T UusitaloRainer Rauramaa
Feb 18, 2005·Journal of Hypertension·Luis MenaTulio Sulbarán
Aug 19, 2005·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Katharina MahnGiovanni E Mann
Aug 26, 2006·Menopause : the Journal of the North American Menopause Society·Patricia S Williamson-HughesMark W Empie
Apr 18, 2007·Hypertension·Mateus C LaterzaMaria U P B Rondon
Feb 9, 2008·Hypertension·Megan CoylewrightPamela Ouyang
Oct 31, 2008·Talanta·M J MoorcroftR G Compton
Mar 10, 2010·Hypertension·Tine W HansenUNKNOWN International Database on Ambulatory Blood Pressure in Relation to Cardiovascular Outcomes Investigators
May 4, 2010·European Journal of Cardiovascular Prevention and Rehabilitation : Official Journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology·Carlos H G SpontonAngelina Zanesco
Feb 12, 2011·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·X X LiuR T Hui
Aug 2, 2011·Archives of Physiology and Biochemistry·Tiago M RezendeAngelina Zanesco
Mar 14, 2012·Arquivos brasileiros de cardiologia·Edimar Alcides BocchiVictor Sarli Issa
Jun 15, 2012·Journal of Science and Medicine in Sport·Andrew D WilliamsMadeleine J Ball
Jan 18, 2013·Journal of Hypertension·Véronique A CornelissenNeil A Smart
Mar 26, 2013·Journal of the American Heart Association·Veronique A Cornelissen, Neil A Smart
Oct 2, 2013·Materia Socio-medica·Semso RosicMuhamed Rosic
Nov 29, 2013·Journal of Human Hypertension·N PagonasT H Westhoff
Apr 22, 2014·American Journal of Physiology. Heart and Circulatory Physiology·Carlos H SpontonAngelina Zanesco
Aug 8, 2014·Revista brasileira de ginecologia e obstetrícia : revista da Federação Brasileira das Sociedades de Ginecologia e Obstetrícia·Lúcio Omar CarmignaniAarão Mendes Pinto-Neto
Aug 12, 2014·The American Journal of Medicine·J Rick TurnerDaichi Shimbo
Aug 28, 2014·European Journal of Pharmacology·Alexander V Sirotkin, Abdel Halim Harrath
Sep 30, 2014·Climacteric : the Journal of the International Menopause Society·M-N ChenC-F Liu
Dec 8, 2016·Blood Pressure Monitoring·Matthew J ZawadzkiWilliam Gerin

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NCT03008785

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