Isolated bone metastasis in testicular germ cell tumors: a case report and review of the literature

Onkologie
Kazim UygunFerda Akbay Harmandar

Abstract

In testicular germ cell tumors (GCT), bone metastases are usually seen late in the disease progress and are almost always associated with involvement of other sites. However, isolated bone metastasis is an extremely rare finding in these patients. A 43- year-old man was admitted to the neurosurgery department of our hospital suffering from dysarthria, ataxia, headaches and a progressive swelling above the parietooccipital region of the skull. Radiological, biochemical and pathologic tests showed that the lesion of the skull was an isolated skull metastasis as an initial manifestation of nonseminomatous GCT of the testis. When a young patient presents with bone pain or painless swelling, even if it is an unusual site and isolated, testicular GCT should be considered as a differential diagnosis, as these lesions could be the first evidence of metastatic GCT.

References

Oct 1, 1988·British Journal of Urology·J C Rhymer, J M Towler
Oct 1, 1988·British Journal of Urology·A K AsthanaM S Agrawal
Dec 1, 1988·British Journal of Cancer·R N HitchinsK D Bagshawe
Sep 1, 1985·Clinical Radiology·C H Collis, H Eckert
Jan 1, 1982·Medical and Pediatric Oncology·E S Henderson
Jan 1, 1982·Medical and Pediatric Oncology·A J ScalzoR Tinsley
Jul 24, 2003·European Urology·Peter AlbersStefan C Müller

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Citations

Feb 22, 2012·Journal of Cancer Research and Clinical Oncology·Karin OechsleFriedemann Honecker
Apr 10, 2010·International Journal of Urology : Official Journal of the Japanese Urological Association·Cyrus ChargariLionel Védrine
Nov 15, 2014·Journal of Cancer Research and Clinical Oncology·Christoph OingKarin Oechsle
Dec 3, 2014·Seminars in Diagnostic Pathology·Thomas M Ulbright, Robert H Young

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