PMID: 11921146Mar 29, 2002Paper

Isolated hallucinosis in Alzheimer's disease is associated with African-American race

International Journal of Geriatric Psychiatry
Medhat M BassionyC G Lyketsos

Abstract

The aim of this investigation was to study the relationship between isolated hallucinosis and race in Alzheimer's disease. This was a cross-sectional, case control study carried out at the Neuropsychiatry Service, outpatient clinic at the Johns Hopkins School of Medicine, USA. The participants were 237 community-residing patients with probable Alzheimer's disease according to NINCDS/ADRDA criteria were included in the study. 9 patients with isolated hallucinosis were compared to a control group of 228 patients who had neither delusions nor hallucinations. Patients with only delusions or both delusions and hallucinations were excluded based on prior research. Patients were assessed clinically for the presence of hallucinations using the DSM-IV glossary definitions. They were also rated on standardized measures of cognitive impairment, depression, functional impairment, and general health. There was a significant association between hallucinations and race in patients with Alzheimer's disease. Before adjustment for other variables, the African-American race conferred a 5.5-fold (95% CI = 1.4-21.6; p = 0.02) increased risk for isolated hallucinosis. After adjustment for multiple other variables, this risk increased further to 27.2...Continue Reading

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Citations

Sep 5, 2003·Psychosomatics·Medhat M Bassiony, Constantine G Lyketsos
Jan 1, 2011·International Journal of Psychiatry in Medicine·Obiora E OnwuamezeSergio Paradiso
May 8, 2002·International Journal of Geriatric Psychiatry
Nov 30, 2005·International Journal of Geriatric Psychiatry·Ajit ShahTade Thompson
Feb 28, 2020·Parkinsonism & Related Disorders·Shi-Rui GanSheng-Han Kuo

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