Isolated Intestinal Ganglioneuroma Mimicking Small Bowel Crohn's Disease

ACG Case Reports Journal
Madhuri BadrinathTed Achufusi


Ganglioneuromas (GNs) are hamartomatous tumors derived from the autonomic nervous system. GNs are frequently associated with neurofibromatosis-1 and multiple endocrine neoplasia type 2b and commonly present with constipation, abdominal pain, weight loss, obstruction, and gastrointestinal bleeding. We report a 40-year-old man with symptoms of chronic abdominal pain, weight loss, and diarrhea for 1 year. Imaging was suggestive of thickening of ileal wall with a stricture, and subsequent biopsy revealed intestinal GN. To our knowledge, this is the first case report of an isolated intestinal GN masquerading as Crohn's disease.


Nov 1, 1975·Archives of Disease in Childhood·P G SwiftF Harris
Apr 22, 2004·AJR. American Journal of Roentgenology·Sridhar R CharagundlaJohn Rombeau
Sep 20, 2007·World Journal of Gastroenterology : WJG·George Van BurenEduardo-A Souchon
Sep 18, 2012·Journal of Medical Case Reports·Enrico FioriPietro Mingazzini
Jun 16, 2015·Case Reports in Gastrointestinal Medicine·George Abraham, Sateesh R Prakash

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