Abstract
Premature restriction or closure of foramen ovale (FO) in otherwise structurally normal hearts may be associated with right ventricular dilation, tricuspid regurgitation, pericardial effusion, heart failure, even poor perinatal outcomes. Data about these rare conditions are lacking. We retrospectively reviewed the echocardiographic records of 9704 fetuses seen from 2010 to 2014 in Beijing Anzhen Hospital, a regional and national referral center, to ascertain the presence of restriction or closure of FO. We collected the fetal echocardiography and perinatal outcome data for this group of fetuses with restriction or closure of FO. In this large, single-institution cohort (n = 9704), 6707 fetuses seen between 23 and 37 weeks of gestation had normal heart structures; of these, 60 (0.89%) had restrictive FO (rFO) and 5 (0.07%) had closure of FO (cFO). Fetal echocardiographic images showed right atrial dilation in 48 (73.84%), right ventricular dilation in 38 (58.46%), tricuspid regurgitation in 19 (29.23%), and pericardial effusion in 10 (15.38%). Also in this group, 50 (83.3%) with rFO and 4 (80.0%) with cFO had follow-up data. No prenatal deaths occurred in either the rFO or the cFO group, but the neonatal mortality included 1 in ...Continue Reading
References
Aug 1, 1991·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·P KachaliaB A Carroll
Oct 1, 1990·American Heart Journal·R N Belkin, J Kisslo
Nov 1, 1988·Journal of Clinical Ultrasound : JCU·P A Stewart, J W Wladimiroff
May 1, 1994·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·E Z PhilliposK D Still
Jan 26, 1999·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·I ShapiroE G Abinader
Mar 9, 1999·Circulation·Y V MaenoL K Hornberger
Aug 10, 1999·Journal of the American College of Cardiology·J RychikT L Spray
Mar 17, 2001·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·T Kiserud, S Rasmussen
Mar 20, 2002·Circulation·Mary T Donofrio
Sep 1, 1991·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·L R FeitC S Kleinman
May 18, 2004·Journal of the American College of Cardiology·Mio TaketazuLisa K Hornberger
Jun 29, 2004·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Jack RychikMary Van Der Veld
Nov 16, 2004·The American Journal of Cardiology·Mary T DonofrioWilliam B Moskowitz
Dec 21, 2004·Fetal Diagnosis and Therapy·A HagenM Entezami
Feb 18, 2011·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Rajesh Punn, Norman H Silverman
Jun 29, 2011·Pediatric Cardiology·Umang GuptaJohn Bokowski
Jun 28, 2013·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Yi-Dan LiYi-Hua He
Mar 4, 2014·Pediatric Cardiology·Orhan UzunMichael J Lewis
Citations
Dec 18, 2019·Cardiology in the Young·Katharina StockTomaž Podnar
Jan 11, 2020·Pediatric Cardiology·Carin WalterJoan Sánchez-de-Toledo
Jul 8, 2020·Medical Sciences : Open Access Journal·Bibhuti B Das
Jan 23, 2020·Scientific Reports·Flora Y WongDietmar Schranz
Mar 10, 2020·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·F VenaD Paladini
Dec 23, 2020·Journal of Investigative Medicine High Impact Case Reports·Jaclyn Michelle KappicoRangasamy Ramanathan
Jul 29, 2021·JACC. Case Reports·Eunice Hahn, Regina Keller
Jul 10, 2021·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Shuang JuYan Fang
Sep 23, 2020·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·L García-OteroF Crispi
Oct 28, 2021·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·Tolga AkbaşNazan Özbarlas
Nov 30, 2021·Journal of Cardiac Surgery·Antonio F CornoJorge D Salazar