Isolated presence of antibody to hepatitis B core antigen in injection drug users: do they need to be vaccinated?

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
Gianluca QuaglioPaolo Mezzelani

Abstract

In a study of 497 injection drug users who had isolated presence of antibody to hepatitis B core antigen (anti-HBc) at the time of enrollment, 404 (81%) retained this condition after a mean of 49 months of follow-up, during which time no new hepatitis B surface antigen marker was detected. These findings support the hypothesis that patients with isolated presence of anti-HBc have strong resistance to reinfection and do not need vaccination.

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Citations

Jun 28, 2003·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Fadel AlhababiC Y William Tong
Oct 24, 2012·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Mallory D WittChloe L Thio
May 15, 2009·International Journal of Environmental Research and Public Health·Fabio LugoboniPaolo Mezzelani
Mar 4, 2005·Enfermedades infecciosas y microbiología clínica·Javier Colomina-RodríguezAntonio Guerrero-Espejo
Dec 14, 2005·Journal of Hepatology·Angelos HatzakisCatherine Haida
Apr 12, 2016·Human Vaccines & Immunotherapeutics·Jun YaoJingjing Ren
Nov 6, 2014·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Emily HenkleUNKNOWN Chronic Hepatitis Cohort Study (CHeCS) Investigators
Jan 11, 2013·Hepatitis Research and Treatment·Arun Kumar JhaSanjeev Saini
Feb 27, 2016·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Audrey L FrenchMarion G Peters
Mar 8, 2017·Human Vaccines & Immunotherapeutics·François-Xavier Catherine, Lionel Piroth

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