PMID: 7237482Mar 2, 1981

Isolation and characterisation of glycopeptides from digests of human Tamm-Horsfall glycoprotein

Carbohydrate Research
A M Afonso


Glycopeptides were isolated from pronase digests of human Tamm-Horsfall glycoprotein and its asialo derivative. The carbohydrate moiety of the major glycopeptide preparation isolated from the former digests had an apparent molecular weight of 4300, and those of two glycopeptides isolated from the latter digests had molecular weights of 3600 and 2300. These data, together with the compositions of the glycopeptides, indicate that the Tamm-Horsfall glycoprotein has at least five asparagine residues substituted by complex carbohydrate moieties, three being of one type, relatively rich in galactose, and two containing more sialic acid but less galactose. A small amount of a mannose-rich glycopeptide was also recovered from the digests of the Tamm-Horsfall glycoprotein.


Jan 1, 1976·Kidney International·F Allen, C C Tisher
Apr 18, 1979·Biochimica Et Biophysica Acta·W van DijkW Ferwerda
Sep 15, 1977·The Biochemical Journal·F Serafini-Cessi
Jan 1, 1976·Annual Review of Biochemistry·C J Waechter, W J Lennarz
Nov 28, 1972·Biochimica Et Biophysica Acta·A J CleaveA R Peacocke
Sep 1, 1972·The American Journal of Cardiology·R KlintM Bloom
Oct 13, 2001·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·C C van der Rijt, L van Zuijlen
Mar 1, 1957·Archives of Biochemistry and Biophysics·H ROSEN
May 1, 1950·Proceedings of the Society for Experimental Biology and Medicine·I TAMM, F L HORSFALL


Jan 13, 1999·Glycobiology·J J van RooijenJ F Vliegenthart
Oct 1, 1992·Zentralblatt für Veterinärmedizin. Reihe A·D C RhodesE C Hawkins
Feb 1, 1990·Kidney International·J K HortonJ D Williams
Jan 25, 2018·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Tsai-Hung WuChang-Youh Tsai
Mar 5, 2011·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Syue-Cian SiaoChia-Li Yu

Related Concepts

UMOD protein, human
Tamm-Horsfall protein

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Alzheimer's Disease: MS4A

Variants within the membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease in genome-wide association studies. Here is the latest research on Alzheimer's disease and MS4A.

Pediculosis pubis

Pediculosis pubis is a disease caused by a parasitic insect known as Pthirus pubis, which infests human pubic hair, as well as other areas with hair including eye lashes. Here is the latest research.

Rh Isoimmunization

Rh isoimmunization is a potentially preventable condition that occasionally is associated with significant perinatal morbidity or mortality. Discover the latest research on Rh Isoimmunization here.

Genetic Screens in iPSC-derived Brain Cells

Genetic screening is a critical tool that can be employed to define and understand gene function and interaction. This feed focuses on genetic screens conducted using induced pluripotent stem cell (iPSC)-derived brain cells. It also follows CRISPR-Cas9 approaches to generating genetic mutants as a means of understanding the effect of genetics on phenotype.

Enzyme Evolution

This feed focuses on molecular models of enzyme evolution and new approaches (such as adaptive laboratory evolution) to metabolic engineering of microorganisms. Here is the latest research.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Pharmacology of Proteinopathies

This feed focuses on the pharmacology of proteinopathies - diseases in which proteins abnormally aggregate (i.e. Alzheimer’s, Parkinson’s, etc.). Discover the latest research in this field with this feed.

Alignment-free Sequence Analysis Tools

Alignment-free sequence analyses have been applied to problems ranging from whole-genome phylogeny to the classification of protein families, identification of horizontally transferred genes, and detection of recombined sequences. Here is the latest research.