PMID: 1195504Oct 1, 1975

Isolation and characterization of a herpesvirus from wild turkeys (Meleagris gallopavo osceola) in Florida

Journal of Wildlife Diseases
H G GrantC F Simpson

Abstract

Viral agents producing both a syncytial-type cytopathic effect and type A intranuclear inclusion bodies in vitro were isolated from the kidneys of five of 10 wild turkeys. A plaque assay system for viral infectivity was developed and used to characterize one of the wild turkey viruses (WTV). WTV replication was inhibited by 5-bromodeoxyuridine, indicating the virus contained DNA as its genetic material. Virus infectivity could be transferred only as viable whole cell preparations; one cycle of rapid freezing and thawing completely inactivated the virus. Typical herpes-like virions were found within the nuclei when cells infected with WTV were examined by electron microscopy. WTV had characteristics typical of the herpes group of viruses.

Citations

Jun 1, 1977·Toxicology and Applied Pharmacology·T Kuiper-GoodmanI C Munro

Related Concepts

Aves
Cytopathogenic Effect, Viral
Thymic Group Viruses
Meleagridinae

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