PMID: 8972725Nov 8, 1996Paper

Isolation and characterization of a human heart cDNA encoding a new member of the small heat shock protein family--HSPL27

Biochimica Et Biophysica Acta
W Y LamM M Waye

Abstract

A novel cDNA clone was isolated from a human adult heart cDNA library. This cDNA clone is similar to the small heat shock protein (smhsp) in both DNA and amino acid sequences, especially in the conserved region. Sequence analysis has shown that the putative novel smhsp, named 27 kDa heat-shock-protein-like protein (HSPL27) is a protein of 241 amino acids with a deduced molecular mass of 26.7 kDa and a deduced pI of 8.0. We have expressed the HSPL27 in E. coli and the expressed protein was found to be present in the soluble fraction of the bacterial cell lysate. Chromosomal mapping data shows that the HSPL27 gene is located at human chromosome 5q11.2.

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Citations

Mar 1, 2005·Journal of Molecular and Cellular Cardiology·Ryan P Taylor, Ivor J Benjamin
Dec 22, 1998·Biochimica Et Biophysica Acta·W C BoelensW W De Jong
Aug 1, 2006·International Journal of Experimental Pathology·Gordon FernsShahida Shafi
Jan 18, 2018·Journal of the Peripheral Nervous System : JPNS·Da E NamKi W Chung
Nov 12, 2019·Molecular Carcinogenesis·Maria-Anna KaliorakiAndreas Scorilas
Jul 3, 1998·International Journal of Biological Macromolecules·W W de JongJ A Leunissen

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