PMID: 11342111May 9, 2001Paper

Isolation and characterization of a human thiamine pyrophosphokinase cDNA

Biochimica Et Biophysica Acta
Kazuto NosakaT Abe

Abstract

A human thiamine pyrophosphokinase cDNA clone (hTPK1) was isolated and sequenced. When the intact hTPK1 open reading frame was expressed as a histidine-tag fusion protein in Escherichia coli, marked enzyme activity was detected in the bacterial cells. The hTPK1 mRNA was widely expressed in various human tissues at a very low level, and the mRNA content in cultured fibroblasts was unaffected by the thiamine concentration of the medium. The chromosome localization of the hTPK1 gene was assigned to 7q34.

References

Apr 1, 1979·Neurochemical Research·J R Cooper, J H Pincus
Sep 16, 1976·Nature·N J Proudfoot, G G Brownlee
Apr 1, 1969·The Journal of Pediatrics·F S PorterJ B Sidbury
Sep 1, 1981·Proceedings of the National Academy of Sciences of the United States of America·T Matsuda, J R Cooper
Sep 27, 1984·The New England Journal of Medicine·H MandelY Naveh
Aug 1, 1996·Mammalian Genome : Official Journal of the International Mammalian Genome Society·M Kozak
Jul 10, 1998·Biochimica Et Biophysica Acta·A Schellenberger
Oct 22, 1998·European Journal of Human Genetics : EJHG·M MustaphaC Petit
Nov 24, 1999·The Journal of Biological Chemistry·K NosakaH Ueyama
Mar 4, 2000·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·H O NghiêmJ P Changeux

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Citations

Jul 6, 2007·Plant Molecular Biology·Imad AjjawiDavid K Shintani
Nov 28, 2013·Cancer & Metabolism·Jason A ZastreStar Ye
Aug 10, 2005·Pediatric Neurology·Mitsuo ToyoshimaKazuo Yamada
Mar 6, 2012·Journal of the Neurological Sciences·Khanh vinh quôc Lu'o'ng, Lan Thi Hoàng Nguyên
May 19, 2016·Expert Review of Neurotherapeutics·Juan Darío Ortigoza-EscobarBelén Pérez-Dueñas
May 5, 2021·Plant Physiology·Simon StrobbeDominique Van Der Straeten

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