Isolation and characterization of a mutant of Escherichia coli blocked in the synthesis of putrescine.

Journal of Bacteriology
I N HirshfieldW K Maas

Abstract

A mutant of Escherichia coli is described which is defective in the conversion of arginine to putrescine. The activity of the enzyme agmatine ureohydrolase is greatly reduced, whereas the activity of the other two enzymes of the pathway, the constitutive arginine decarboxylase and the inducible arginine decarboxylase, are within the normal range. The growth behavior of the mutant reflects the enzymatic block. It grows well in the absence of arginine, but only poorly in the presence of arginine. Under the former conditions, putrescine can be formed from ornithine as well as arginine, whereas under the latter conditions, because of feedback control, it can be formed only from arginine.

References

Feb 1, 1968·Journal of Bacteriology·E Dubnau, W K Maas
Mar 1, 1970·Journal of Bacteriology·D R Morris, C M Jorstad
Apr 1, 1960·Journal of General Microbiology·B N AMESL A HERZENBERG
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Citations

Jan 1, 1976·Antonie van Leeuwenhoek·J N Lopes, F S Cruz
Mar 15, 1973·European Journal of Biochemistry·G Turnock, B Birch
Jan 1, 1972·Molecular & General Genetics : MGG·W K Maas
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Dec 1, 2004·EcoSal Plus·Daniel Charlier, Nicolas Glansdorff
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Feb 1, 1980·Journal of Bacteriology·C M JorstadD R Morris
Feb 1, 1976·Journal of Bacteriology·H J Rosenfeld, J Roberts
Jan 1, 1985·Advances in Enzyme Regulation·O Heby
Jun 1, 1974·Bacteriological Reviews·M Slater, M Schaechter
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Dec 1, 1973·Journal of Bacteriology·G F Munro, C A Bell
Jan 1, 1981·The International Journal of Biochemistry·G IllianoG Paolisso
Mar 1, 1970·Journal of Bacteriology·D R Morris, C M Jorstad
Dec 1, 1975·Journal of Bacteriology·I D AlgranatiW K Maas
Dec 1, 1975·Journal of Bacteriology·M B Ritchey, E A Delwiche
Apr 25, 1977·Biochemical and Biophysical Research Communications·I D Algranati, S H Goldemberg
Oct 9, 1970·Biochemical and Biophysical Research Communications·C W Tabor, H Tabor
Jan 1, 1981·Differentiation; Research in Biological Diversity·O Heby

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