Isolation and characterization of a spiral bacterium from the crypts of rodent gastrointestinal tracts.

Applied and Environmental Microbiology
M W Phillips, A Lee

Abstract

Spiral-shaped bacteria with a distinctive morphology were isolated from the intestinal mucosa of rats and mice on a campylobacter selective medium using microaerophilic incubation. These bacteria have been shown by other authors to be present in the intestinal tracts of several animal species but have not been cultured previously. The results of electron microscopic examinations and biochemical testing have shown that these organisms do not correspond to any known genus. Colonization experiments with pure cultures in gnotobiotic rodents have shown these bacteria to be mucosa associated, with a particular affinity for intestinal crypts. The pattern of colonization of the intestinal crypts in gnotobiotes known to be free of other mucosa-associated organisms differed from the colonization occurring in conventional animals that possess a normal mucosa-associated flora.

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Citations

Jan 1, 1991·Scandinavian Journal of Gastroenterology. Supplement·A Lee
Nov 1, 1992·Veterinary Pathology·A LeeJ C Murphy
Jan 1, 1996·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·S L Hazell
Apr 1, 1986·Journal of Clinical Pathology·C S GoodwinB J Marshall
Jan 9, 2001·Clinical Microbiology Reviews·J V Solnick, D B Schauer
Jul 1, 1993·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·C A Kirkbride
Sep 15, 2020·World Journal of Gastroenterology : WJG·Rasha Raheem AlkarkoushiTraci L Testerman
Mar 1, 1989·Microbial Ecology·H M Cowley, R H Hill
Mar 31, 1999·Comparative Immunology, Microbiology and Infectious Diseases·L Zenner
Jan 1, 1988·Journal of Clinical Microbiology·S RomeroR F Schell
May 1, 1993·Infection and Immunity·A LeeS Hazell
Apr 1, 1996·Journal of Clinical Microbiology·L K RileyC Besch-Williford
Oct 1, 1993·Journal of Clinical Microbiology·D B SchauerS Falkow
Nov 1, 1988·Infection and Immunity·A LeeS Kouprach

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