PMID: 2495539Apr 1, 1989Paper

Isolation and characterization of an olfactory mutant in Drosophila with a chemically specific defect

Proceedings of the National Academy of Sciences of the United States of America
S L Helfand, J Carlson

Abstract

A Drosophila mutant was isolated and shown to exhibit defective response to the chemical odorant benzaldehyde in two distinctly different behavioral assays. The defect exhibited chemical specificity: response to three other chemicals was normal. The mutant also showed abnormalities in pigmentation and fertility. Genetic mapping and complementation analysis provide evidence that the olfactory, pigmentation, and fertility defects arise as a result of a lesion at the pentagon locus. The specificity of the olfactory defect suggests the possibility that the mutation may define a molecule required in reception, transduction, or processing of a specific subset of chemical information in the olfactory system.

References

May 1, 1976·Proceedings of the National Academy of Sciences of the United States of America·Y DudaiS Benzer
May 1, 1985·Proceedings of the National Academy of Sciences of the United States of America·J PevsnerS H Snyder
Jun 19, 1986·The New England Journal of Medicine·U C Dräger
Sep 1, 1984·Behavior Genetics·L Tompkins
Mar 1, 1984·Proceedings of the National Academy of Sciences of the United States of America·Z Chen, D Lancet

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Citations

Oct 1, 1990·Cell and Tissue Research·R F StockerK F Fischbach
Oct 23, 1998·Invertebrate Neuroscience : in·P ClyneJ R Carlson
Oct 1, 1998·Behavioural Brain Research·G O Pflugfelder
Oct 15, 2003·Behavioural Processes·Jean Marc Devaud
Aug 1, 1996·Current Opinion in Neurobiology·D P Smith
Oct 1, 1989·Proceedings of the National Academy of Sciences of the United States of America·M McKennaJ Carlson
Nov 1, 1990·Proceedings of the National Academy of Sciences of the United States of America·G Hasan
Jun 25, 1991·Proceedings of the National Academy of Sciences of the United States of America·R K Ayer, J Carlson
Jul 10, 2009·Proceedings. Biological Sciences·Ayse YaraliBertram Gerber
Sep 19, 2006·Learning & Memory·David-Benjamin G AkalalRonald L Davis
Jul 28, 2012·The Journal of Experimental Biology·Sara WassermanMark A Frye
Oct 23, 2013·PloS One·Nathan LuebberingVaughn Cleghon
Jun 10, 1997·Proceedings of the National Academy of Sciences of the United States of America·B RoginaS L Helfand
Aug 2, 2001·Proceedings of the National Academy of Sciences of the United States of America·K F Störtkuhl, R Kettler
Dec 25, 2009·Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology·Marien de BruyneCoral G Warr
Nov 1, 1994·Trends in Neurosciences·A Ferrús, I Canal
Jun 30, 2009·Journal of Insect Physiology·Jacob RiveronEsther Alcorta
May 21, 2013·Genes, Brain, and Behavior·E B BrownS M Rollmann
Dec 5, 1992·Journal of Molecular Biology·C M OgataS H Kim
Jun 30, 1992·Biochemistry·B A Bahr, S M Parsons
Aug 1, 1990·Journal of Neurogenetics·C AyyubO Siddiqi
Nov 15, 2017·BMC Genomics·Elizabeth B BrownStephanie M Rollmann
May 23, 1991·Nature·D Lancet
Feb 3, 2019·Behavior Genetics·Elizabeth B BrownStephanie M Rollmann
Oct 4, 2018·Analytical and Bioanalytical Chemistry·Olivia LeitchAlisha Anderson
Nov 2, 2019·The Journal of Experimental Biology·Srinivas Gorur-ShandilyaThierry Emonet
Jan 21, 2021·Communications Biology·Budhaditya ChowdhuryHerman A Dierick
Jan 9, 2003·The Journal of Experimental Biology·Marcus C StensmyrBill S Hansson
Apr 19, 2013·The Journal of Experimental Biology·Dushyant MishraBertram Gerber
Jul 1, 2006·The Journal of Experimental Biology·Cécile FaucherMarien de Bruyne
Jul 1, 1997·Learning & Memory·A Guo, K G Götz

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